首页 | 本学科首页   官方微博 | 高级检索  
检索        


TDCS guided using fMRI significantly accelerates learning to identify concealed objects
Authors:Clark Vincent P  Coffman Brian A  Mayer Andy R  Weisend Michael P  Lane Terran D R  Calhoun Vince D  Raybourn Elaine M  Garcia Christopher M  Wassermann Eric M
Institution:
  • a Mind Research Network, Albuquerque, NM 87106, USA
  • b Department of Psychology, University of New Mexico, Albuquerque, NM 87131, USA
  • c Department of Computer Science, University of New Mexico, Albuquerque, NM 87131, USA
  • d Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM 87131, USA
  • e Sandia National Laboratories, Albuquerque, NM 87123, USA
  • f National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
  • Abstract:The accurate identification of obscured and concealed objects in complex environments was an important skill required for survival during human evolution, and is required today for many forms of expertise. Here we used transcranial direct current stimulation (tDCS) guided using neuroimaging to increase learning rate in a novel, minimally guided discovery-learning paradigm. Ninety-six subjects identified threat-related objects concealed in naturalistic virtual surroundings used in real-world training. A variety of brain networks were found using functional magnetic resonance imaging (fMRI) data collected at different stages of learning, with two of these networks focused in right inferior frontal and right parietal cortex. Anodal 2.0 mA tDCS performed for 30 min over these regions in a series of single-blind, randomized studies resulted in significant improvements in learning and performance compared with 0.1 mA tDCS. This difference in performance increased to a factor of two after a one-hour delay. A dose-response effect of current strength on learning was also found. Taken together, these brain imaging and stimulation studies suggest that right frontal and parietal cortex are involved in learning to identify concealed objects in naturalistic surroundings. Furthermore, they suggest that the application of anodal tDCS over these regions can greatly increase learning, resulting in one of the largest effects on learning yet reported. The methods developed here may be useful to decrease the time required to attain expertise in a variety of settings.
    Keywords:Perception  Attention  Memory  Functional magnetic resonance imaging  Expertise  Training  Transcranial direct current stimulation  Frontal cortex  Parietal cortex  Medial temporal lobe  Cingulate cortex
    本文献已被 ScienceDirect PubMed 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号