闽东畲族自然人群体液免疫球蛋白和补体C3、C4水平调查

目的对闽东地区畲族自然人群体液免疫指标水平进行调查,并比较畲族人群与汉族人群免疫指标水平的差别。方法采用免疫比浊法分别对279例闽东地区畲族自然人群和104例汉族自然人群血清免疫球蛋白IgG、IgA、IgM和补体C3、C4水平进行检测。分析不同性别、年龄的畲族自然人群间体液免疫指标水平的差异,并与汉族人群进行比较。结果畲族自然人群血清IgG水平女性（14.55±3.06）g/L]高于男性（13.49±2.84）g/L]（P〈0.05）,IgA、IgM和C3、C4的水平与性别无关（P〉0.05）;IgG、IgA、IgM的水平与年龄无关（P〉0.05）,而C3、C4随年龄的增长水平升高（P〈0.05）。畲族人群的免疫球蛋白IgG、IgA、IgM水平在各年龄段均高于汉族人群（P〈0.05）,畲族人群的C3、C4水平与汉族人群无明显差异（P〉0.05）。结论畲族人群的体液免疫指标中IgG、IgA、IgM水平高于汉族人群。

Investigation of the immunoglobin and complement C3,C4 levels of Shes Mindong region

Objective To investigate the levels of immunoglobin and complement of a natural population of Shes in eastern Fu- jian province,and compare the immune indicators leveles in Shes and Hans.Methods Immunoturbidimetric assay was used to detect serum leves of immunoglobulin IgG,IgA,IgM and complement C3,C4 for 279cases Shes and 104 cases Hans natural populations in eastern Fujian Provine,who were grouped according to age and gender.The different levels of humoral immunity between the groups were analyzed and compared with the Hans healthy population to prove whether natural populations in eastern Fujian Pro- vine have distinct level of humoral immune.Results For the natural population of Shes,serum IgG levels in females（14.55± 3.06）g/L]was higher than males（13.49±2.48）g/L]（P〈0.05）,IgA,IgM and C3,C4 levels had nothing to do with gender（P〈0.05）,and the level of immunoglobulin IgG,IgA and IgM was not significantly changed with age（P〈0.05）,but C3 and C4 levels increased（P〈0.05）.Conclusion The immunoglobulins of IgG,IgA and IgM levels in all ages of Shes were higher than Han popu- lation and the levels of C3,C4 are not different from Han population.