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尿NMP22、UBC及BTA联合检测在膀胱癌早期诊断中的意义研究
引用本文:李扬,郑衍平,许旭昀,张敬成,卢小卓.尿NMP22、UBC及BTA联合检测在膀胱癌早期诊断中的意义研究[J].国际检验医学杂志,2011,32(11):1187-1188,1190.
作者姓名:李扬  郑衍平  许旭昀  张敬成  卢小卓
作者单位:1. 广东省汕头市中医医院检验科,515031
2. 汕头大学医学院附属第一医院内科,广东汕头,515041
3. 暨南大学附属第四医院检验科,广州,510220
基金项目:广东省医学科研基金专项课题
摘    要:目的 评价膀胱癌抗原核基质蛋白22(NMP22)、尿膀胱癌抗原(UBC)、膀胱肿瘤抗原(BTA)在诊断膀胱癌中的应用价值.方法 应用酶联免疫吸附实验,检测膀胱癌疑似患者尿中NMP22、UBC、BTA的水平,并与健康组进行对比,评价NMP22、UBC、BTA的诊断价值.结果 膀胱癌患者 3项标志物联合检测敏感性96.9...

关 键 词:核基质蛋白质类  膀胱肿瘤  抗原

The significance of NMP22,UBC and BTA in the early diagnosis of bladder cancer*
Li Yang,Zheng Yanping,Xu Xuyun,Zhang Jingchen,Lu Xiaozhuo.The significance of NMP22,UBC and BTA in the early diagnosis of bladder cancer*[J].International Journal of Laboratory Medicine,2011,32(11):1187-1188,1190.
Authors:Li Yang  Zheng Yanping  Xu Xuyun  Zhang Jingchen  Lu Xiaozhuo
Institution:Li Yang1,Zheng Yanping1,Xu Xuyun1,Zhang Jingchen2,Lu Xiaozhuo3(1.Shantou Hospital of Traditional Chinese Medicine,Guangdong 515031,China,2.Shantou Guangdong 515041,3.Guangzhou 510220,China)
Abstract:Objective To evaluate the clinical value of NMP22,UBC and BTA in the early diagnosis of bladder cancer.Methods Enzyme-linked immunosorbent assay was used to detect the concentration of NMP22,UBC and BTA in the urine of suspected patients,and the detected results were compared with that of healthy controls.Results The sensitivity,specificity and positive predictive value of the combination of NMP22,UBC and BTA in diagnosis of bladder cancer were 96.9%(33/34),80%(20/25) and 92.5%,and were higher of that any s...
Keywords:nuclear matrix-associated proteins  urinary bladder neoplasms  antigens  
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