厄贝沙坦氢氯噻嗪片治疗高血压的临床效果

目的探讨厄贝沙坦氢氯噻嗪片治疗高血压的临床效果。方法选取我院收治的200例高血压患者作为研究对象,采用随机数字表法分为参照组(100例,厄贝沙坦片)和试验组(100例,厄贝沙坦氢氯噻嗪片)。比较两组患者的治疗效果。结果治疗后,两组的收缩压、舒张压及CRP水平均降低,且试验组明显低于参照组(P<0.05)。治疗后,两组的血液流变学指标比较,差异均无统计学意义(P>0.05)。试验组的治疗总有效率明显高于参照组(P<0.05)。两组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论厄贝沙坦氢氯噻嗪片治疗高血压的临床效果显著,具有良好的降压及抗炎效果,且不会对血液流变学指标产生明显影响,安全性较高。

Clinical effect of irbesartan and hydrochlorothiazide tablets in the treatment of hypertension

Objective To explore the clinical effect of irbesartan and hydrochlorothiazide tablets in the treatment of hypertension.Methods A total of 200 patients with hypertension in our hospital were selected as the research objects and divided into reference group(100 cases,irbesartan tablets)and experimental group(100 cases,irbesartan and hydrochlorothiazide tablets)by random number table method.The therapeutic effects of the two groups were compared.Results After treatment,the systolic blood pressure,diastolic blood pressure and CRP level in the two groups decreased,and those in the experimental group were significantly lower than the reference group(P<0.05).After treatment,there were no significant differences in hemorheology indexes between the two groups(P>0.05).The total effective rate of treatment in the experimental group was significantly higher than that in the reference group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Irbesartan and hydrochlorothiazide tablets in the treatment of hypertension has a significant clinical effect,with good antihypertensive and anti-inflammatory effects,and don’t have a significant impact on hemorheology indexes,with a high safety.