七叶皂甙对高血压脑出血患者脑血流量的影响

目的：D一叶皂甙治疗高血压脑出血的疗效和对患者脑血流量的影响。方法：70例脑出血患者随机分为2组（各35例），对照组常规治疗，治疗组加用七叶皂甙20mg溶于生理盐水500ml中静滴，每日1次，共10日。2组降压、抗感染等治疗相同。治疗前及3周后均测定患者的脑血流量和血液流变学变化。结果：治疗3周后，治疗组有总有效率（94．3％）高于对照组（77．1％），P＜0．05，2组脑血流量和血液流变性虽均明显改善，但以七叶皂甙组尤佳，且颅内血肿吸收优于对照组。结论：七叶皂甙可有效治疗高血压脑出血。

Effect of

Objective:To study the influence of βaescin natrum on cerebral blood flow(CBF) in patients with cerebral hemorrhage and the c urative effects.Methods:Seventy cases with acute cerebral hemorrhage were randomly divided into two grou ps.The control group(n=35) was treated with conventional therapy while the t reatment group(n=35) based on the same therapy as control group the βaescin natrum 20 mg+normal saline 500 ml infused intravenously once a day were used for 10 days.In addition the same hypotensive,hypoglycemic and antiinfectious therapies were given to both groups.Before and after therapy th e volume of CBF and the blood rheology were detected.Results:After 3 weeks therapy the total effective rate was 94.3% in treatment group but it was 77.1% in control group.In comparison between two groups the difference was significant(P<0.05).The volume of CBF and blood rheology in both two g roups showed obvious improvements but in treatment group they were the best.Conclusions:The treatment with βaescin natrum combined with conventional therap y for cerebral hemorrhage is superior to that with conventional therapy alone.