血塞通注射液联合降纤酶治疗急性脑梗死31例疗效观察

目的 :观察联用血塞通注射液和降纤酶治疗急性脑梗死的疗效。方法 :62例急性脑梗死患者随机分为 2组。西医组 ( 3 1例 )给予降纤酶 (东菱克栓酶 ) 10 U加入生理盐水 10 0 m l静滴 ,每日 1次 ,3日后改为降纤酶5 U加生理盐水 10 0 m l静滴 ,每日 1次 ,治疗 2日。中西医结合组 ( 3 1例 )在西医组治疗基础上加用血塞通注射液 4 0 0 mg加生理盐水 2 5 0 m l静滴 ,每日 1次 ,共 10日。此外 ,2组均给予降压、控制血糖、抗感染等治疗。治疗前后均测定脑血流量、脑电图、血液流变性等。结果 :治疗 2周后 ,中西医结合组和西医组总有效率分别为96.8%和 67.7% ,2组有显著性差异 ( P<0 .0 1)。 2组脑血流量、脑电图和血液流变性虽均明显改善 ,但以中西医结合组为佳。结论 :血塞通注射液联合降纤酶治疗急性脑梗死疗效优于单用降纤酶

Observation on curative effects of treatment with panax notoginsenoside injection combined with batroxobin for acutely cerebral infarction in 3 1patients

Objective:To study the curative effects of panax notoginsenoside injection combined with ba- troxobin on acutely cerebral infarction ( ACI) .Methods:62 patients with ACI were randomly divided into two groups.The western medicine( WM) group( n=3 1) was treated with batroxobin10 U normal saline10 0 ml infused intravenously once a day for three days then batroxobin 5 U norm al saline 10 0 ml infused once a day for two days while in the integrated traditional Chinese medicine ( TCM) and western medicine ( WM) group ( TCM WM,n=3 1) based on the sam e therapy as WM group the panax notoginsenoside injection 4 0 0 mg normal saline 2 5 0 ml infused intravenously once a day were used for 10 days.In addition the hypertensive, glycem ic control and anti infectious therapies were given to both two groups.Before and after therapy the vol- ume of cerebral blood flow,the electroencephalograph( EEG) ,and the blood rheology were detected.Results:: After two week therapy the total effective rate was 96.8% in TCM WM group but it was 67.7% in WM group.In comparison between two groups the difference was significant ( P <0 .0 1) .The volume of cerebral blood flow,the EEG,and the blood rheology in both two groups showed obvious im provem ents but in TCM WM group they were the best.Conclusions:The treatm ents with panax notoginsenoside injection combined with batroxobin for ACI are superior to that with batroxobin alone.