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61例腹腔手术后继发出血的临床分析:单中心回顾性研究
引用本文:阴海鑫,陈伟杰,何小东.61例腹腔手术后继发出血的临床分析:单中心回顾性研究[J].协和医学杂志,2019,10(4):336-341.
作者姓名:阴海鑫  陈伟杰  何小东
作者单位:1.中国医学科学院 北京协和医学院研究生院,北京 100005
基金项目:国家自然科学基金面上项目81372578中国医学科学院医学与健康科技创新工程2017-12M-4-003
摘    要:  目的  探讨腹腔手术后继发出血的原因和干预时机,以优化治疗方案。  方法  回顾性分析北京协和医院2013年1月至2018年12月腹腔手术后继发出血患者的临床资料,分析出血原因、治疗方案及预后情况。  结果  61例符合纳入和排除标准的腹腔手术后继发出血患者入选本研究,其中男性49例,女性12例,以胰十二指肠切除术患者最多(50.8%,31/61),其次为肝脏手术(16.4%,10/61)和胃部手术(14.8%,9/61)。56例患者明确了出血原因,其中创面渗血和/或创面小动脉活动性出血24例(42.9%,24/56),吻合口出血11例(19.6%,11/56)。出血后多数患者采取手术止血(65.6%,40/61),成功率为87.5%;其次采取介入栓塞止血(24.6%,15/61),成功率为26.7%,差异具有统计学意义(P<0.01)。成功止血55例、死亡5例,1例患者放弃治疗。  结论  腹腔大手术后出血机率更高,手术止血效果可能优于介入栓塞止血。

关 键 词:腹腔手术    出血    出血再手术    介入栓塞
收稿时间:2019-03-07

Clinical Analysis of 61 Patients with Postoperative Hemorrhage after Abdominal Surgery: A Single-center Retrospective Study
Institution:1.Graduate School, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China2.Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Abstract:  Objective  The aim of this study was to explore the causes of postoperative rebleeding after abdominal surgery and the timing of intervention, so as to optimize the treatment plan.  Methods  The clinical data of patients with abdominal bleeding after abdominal surgery from January 2013 to December 2018 were retrospectively collected in Peking Union Medical College Hospital. The causes of bleeding, treatment plan, and prognosis were analyzed.  Results  A total of 61 patients with postoperative hemorrhage after abdominal surgery who met the inclusion and exclusion criteria were enrolled in this study, including 49 males and 12 females. Among them, most patients had pancreaticoduodenectomy (50.8%, 31/61), followed by liver surgery (16.39%, 10/61) and gastric surgery (14.8%, 9/61). The causes of bleeding were identified in 56 patients, including 24 cases of wound bleeding and/or arteriolar active bleeding (42.9%, 24/56) and 11 cases of anastomotic bleeding (19.6%, 11/56). After hemorrhage, most patients (65.6%, 40/61) underwent surgical hemostasis, with a success rate of 87.50%; hemostasis by interventional embolization was adopted in the other patients(24.6%, 15/61), with a success rate of 26.7%(P > 0.01). Successful hemostasis was achieved in 55 cases. Five cases died, and one gave up treatment.  Conclusions  Major abdominal surgery increases hemorrhage risk. Hemostasis of surgery may be superior to that of interventional embolization.
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