双侧太田痣的临床特点

  目的  探讨双侧太田痣的临床特点。  方法  收集1998年1月至2012年6月间在北京协和医院皮肤科就诊的双侧太田痣患者59例, 回顾性分析其发病年龄、性别、皮疹范围、是否双侧对称、皮疹颜色、巩膜是否受累、是否有合并症及特殊病例等, 其中部分病例进行组织病理检查和调Q紫翠宝石激光治疗。  结果  双侧太田痣患者占同时期太田痣患者的4.47%, 均为先天发病, 男:女=1:4.9。患者皮疹颜色为蓝褐色25例, 淡褐色34例; 皮疹双侧对称分布者47例, 双侧不对称者12例; 17例患者累及双侧3支三叉神经; 在皮疹双侧对称分布的患者中有5例患者皮疹为居中分布; 31例患者出现巩膜受累; 4例患者出现先天性血管畸形。组织病理与单侧太田痣无差异, 调Q紫翠宝石激光治疗效果好。  结论  双侧太田痣为一种先天发病的疾病, 有较高的概率出现大面积累及、巩膜受累和合并症。

Clinical Characteristics of Bilateral Nevus of Ota in 59 Patients

Objective To summarize the clinical characteristics of bilateral nevus of Ota. Methods The clinical data of 59 patients with bilateral nevus of Ota who were treated in our department from January 1998 to June 2012 were retrospectively analyzed. In addition to routine clinical observations including age of onset, gender, color of skin rashes, range of skin lesions, existence of bilateral symmetry, and complications, some patients also received pathological examinations and Q-switched alexandrite laser treatment. Results These 59 cases of bilateral nevus of Ota accounted for 4. 47% of the patients with nevus of Ota. All of these cases were congenital, with a male：female ratio of 1：4.9. The color of skin rashes was blue brown in 25 patients and light brown in 34 patients. Bilateral symmetry was found in 47 patients. Seventeen patients had bilateral trigeminal nerve involvement. Among patients with bilateral symmetry, the lesion was centered in 5 patients. Scleral involvement existed in 31 patients. In addition, there were 4 patients with congenital vascular malformation. Pathology of bilateral nevus of Ota showed no difference from that of unilateral nevus of Ota. Q-switched alexandrite laser treatment showed good effectiveness. Conclusion Bilateral nevus of Ota, as a congenital disease, is prone to large area involvement, scleral involvement, and complications.