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维生素A、D、E对0~3岁反复呼吸道感染患儿治疗效果的影响和社区卫生服务干预措施分析
引用本文:张金凤,王雅歆,姚俊彦,胡川,康翠英,王炜华,刘丽晓.维生素A、D、E对0~3岁反复呼吸道感染患儿治疗效果的影响和社区卫生服务干预措施分析[J].检验医学与临床,2020,17(7):910-913.
作者姓名:张金凤  王雅歆  姚俊彦  胡川  康翠英  王炜华  刘丽晓
作者单位:上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399;上海市浦东医院儿科,上海 201399
基金项目:上海市浦东新区卫生和计划生育委员会学科建设主攻课题;国家卫生和计划生育委员会医药卫生科技发展研究中心课题
摘    要:目的探讨维生素A、D、E对0~3岁反复呼吸道感染患儿治疗效果的影响,并分析社区卫生服务对疾病防治的相关干预措施。方法选取2018年2月至2019年2月在该院儿科就诊的125例反复呼吸道感染患儿为观察组;将同期体检身体健康的150例儿童设为对照组。检测所有研究对象血清维生素A、25-羟基维生素D 325(OH)D 3]、维生素E水平,比较两组维生素水平是否存在差异。将观察组中接受常规治疗的患儿设为A组,将接受常规联合维生素治疗的患儿设为B组,比较两组治疗效果。总结儿童反复呼吸道感染防治的社区卫生服务干预措施。结果观察组患儿血清维生素A、25(OH)D 3、维生素E水平均低于对照组健康儿童,维生素缺乏率高于对照组,差异均有统计学意义(P<0.05)。经积极抗感染等对症治疗,A组与B组患儿血清免疫球蛋白(IgA、IgG、IgM)水平均有所提高,B组3种免疫球蛋白水平高于A组,差异均有统计学意义(P<0.05);B组患儿发热、咳嗽、扁桃体肿大及肺部啰音症状消失时间均短于A组,不良反应发生率、复发率低于A组,差异有统计学意义(P<0.05)。结论0~3岁低龄患儿反复呼吸道感染发生率较高,维生素A、D、E缺乏是导致患儿发生反复呼吸道感染的重要原因,常规抗感染同时补充维生素可提高治疗效果,社区卫生服务工作需加强低龄儿童营养状况监测,及时补充维生素A、D、E以提高儿童免疫力,预防呼吸道感染的发生。

关 键 词:维生素  反复呼吸道感染  儿童  社区卫生服务  干预措施

Effects of vitamins A,D and E in the treatment of repeated respiratory tract infection in children aged 0-3 years and the intervention measures of community health services
ZHANG Jinfeng,WANG Yaxin,YAO Junyan,HU Chuan,KANG Cuiying,WANG Weihua,LIU Lixiao.Effects of vitamins A,D and E in the treatment of repeated respiratory tract infection in children aged 0-3 years and the intervention measures of community health services[J].Laboratory Medicine and Clinic,2020,17(7):910-913.
Authors:ZHANG Jinfeng  WANG Yaxin  YAO Junyan  HU Chuan  KANG Cuiying  WANG Weihua  LIU Lixiao
Institution:(Department of Pediatrics,Pudong Hospital,Shanghai 201399,China)
Abstract:Objective To investigate the effects of vitamin A,D,E and in the treatment of repeated respiratory tract infection in children aged 0-3 years,and to analyze the intervention measures of community health services on disease prevention and treatment.Methods A total of 125 children with recurrent respiratory tract infection who were admitted to the pediatric department of our hospital from February 2018 to February 2019 were selected.And 150 healthy children were set as control group.Serum levels of vitamin A,25 hydroxy vitamin D 325(OH)D 3]and vitamin E in fasting venous blood samples were detected.In the observation group,children received routine treatment was selected as group A and children received routine combined vitamin therapy was selected group B.The therapeutic effects of the two groups were compared.The intervention measures of community health service for prevention and treatment of repeated respiratory tract infection in children were summarized.Results Serum levels of vitamin A,25(OH)D 3 and E in the observation group were significantly lower than those in the control group(P<0.05),and the detection rate of deficiency was significantly higher than that in the control group(P<0.05).After symptomatic treatment such as active anti-infection,serum immunoglobulin(IgA,IgG,IgM)levels in group A and group B were improved,and IgA,IgG and IgM of group B were significantly higher than that of group A(P<0.05).In group B,the resolution time of fever,cough,tonsil enlargement and pulmonary rale of group B were significantly shorter than that of group A(P<0.05),and the incidence and recurrence rates of adverse reactions were lower than those in group A(P<0.05).Conclusion Rates of recurrent respiratory tract infections in children aged 0-3 years old are relatively higher,deficiency of vitamin A,D,E is the important reason for the increased risk of the disease.Conventional treatment combined vitamin supplements can effectively improve the immune function,shorten the treatment time,reduce the adverse reaction and recurrence.Community health service needs enhancing young children′s nutritional status monitoring.Timely supplement vitamin could improve children′s immunity,prevent the happening of the respiratory tract infection.
Keywords:vitamin  recurrent respiratory infections  children  community health services  interventions
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