血清鳞状细胞癌相关抗原与宫颈癌病理类型之间的相关性

目的 探讨血清鳞状细胞癌相关抗原(SCC-Ag)与宫颈癌病理类型之间的相关性,评价血清SCC-Ag检测在宫颈癌诊断中的临床应用价值.方法 收集88例宫颈癌患者和103例健康体检者血液标本和资料;采用酶联免疫法测定所有对象血清SCC-Ag水平.分析血清SCC-Ag与宫颈癌病理类型之间的关系.结果 88例宫颈癌中,鳞癌37例、腺癌31例、腺鳞癌20例.与健康对照组比较,各病例组肿瘤标志物水平均有明显升高(P＜0.05).SCC-Ag水平为鳞癌大于腺癌大于腺鳞癌(P＜0.05).结论 血清SCC-Ag与宫颈癌病理类型存在相关性,血清SCC-Ag检测有利于鳞癌的检出.

Relativity between serum SCC-Ag and pathological types of cervical cancer

Objective To investigate the relationship between serum level of squamous cell carcinoma antigen（SCC-Ag） and the pathological types of cervical cancer and to evaluate the application value of SCC-Ag in the diagnosis of cervical cancer. Methods The blood samples and the data in 88 cases of cervical cancer（experimental group） and 103 healthy individuals（control group） were collected.The serum SCC-Ag level was detected by enzyme-linked immunosorbent assay for analyzing the relationship between SCC-Ag and the pathological types of cervical cancer. Results Among 88 cases of cervical cancer,37 cases were squamous cancer,31 cases were adenocarcinoma and 20 cases were adenosquamous carcinoma.Compared with the control group,the levels of tumor markers in various types of experimental groups were significantly increased（P0.05）.The serum SCC-Ag levels showed that squamous cancer adenocarcinoma adenosquamous cancer（P0.05）. Conclusion Serum SCC-Ag has the relativity with the pathological types of cervical cancer.The detection of serum SCC-Ag is conducive to the diagnosis of squamous cancer.