| 南京及周边地区糖化血红蛋白诊断糖尿病的截点值 |
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| 引用本文： | 朱芝娴,李思洋,朱小飞.南京及周边地区糖化血红蛋白诊断糖尿病的截点值[J].检验医学与临床,2019,16(10):1317-1320. |
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| 作者姓名： | 朱芝娴 李思洋 朱小飞 |
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| 作者单位： | 南京中医药大学附属医院检验科,江苏南京,210029;南京中医药大学附属医院检验科,江苏南京,210029;南京中医药大学附属医院检验科,江苏南京,210029 |
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| 摘 要： | 目的研究南京及其周边地区糖化血红蛋白(HbA1c)应用于糖尿病及糖调节受损(IGR)筛查与诊断的可行性,并预测其最佳的诊断截点值。方法将该院就诊的糖尿病患者及糖尿病高危人群共2 767例作为研究对象,行葡萄糖耐量试验,用空腹血糖及糖耐量试验2h血糖进行分组,检测HbA1c,并利用受试者工作特征曲线寻找诊断最佳截点值。结果南京及其周边地区健康、糖尿病及IGR人群的HbA1c比较,差异均有统计学意义(P<0.05),且随着病情的严重程度,HbA1c结果呈上升趋势。HbA1c诊断糖尿病的最佳截点值为6.45%,而诊断IGR的最佳截点值为6.05%。结论南京及其周边地区可以尝试采用6.05%与6.45%分别作为HbA1c诊断IGR与糖尿病的截点值。
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| 关 键 词： | 糖尿病 糖调节受损 糖化血红蛋白 诊断截点值 |
Study on cut-off point of glycosylated hemoglobin in diagnosis for diabetes mellitus in Nanjing and its surrounding areas |
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| ZHU Zhixian,LI Siyang,ZHU Xiaofei.Study on cut-off point of glycosylated hemoglobin in diagnosis for diabetes mellitus in Nanjing and its surrounding areas[J].Laboratory Medicine and Clinic,2019,16(10):1317-1320. |
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| Authors: | ZHU Zhixian LI Siyang ZHU Xiaofei |
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| Institution: | (Department of Clinical Laboratory,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China) |
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| Abstract: | ZHU Zhixian;LI Siyang;ZHU Xiaofei(Department of Clinical Laboratory,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China) |
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| Keywords: | diabetes mellitus impaired glucose regulation glycosylated hemoglobin diagnostic cut-off point |
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