儿童反复呼吸道感染影响因素分析

目的 探讨儿童反复呼吸道感染(RRTIs)的相关影响因素,为儿童RRTIs的有效防治提供依据和策略.方法 选择183例RRTIs患儿纳入病例组,85例同期门诊体检健康儿童纳入对照组,对以上所有儿童可能导致RRTIs的相关因素进行临床资料调查,并对血清微量元素铁、锌、钙、铜,血清25-羟维生素D[25-(OH)-D]水平...

Analysis of the influence factors of repeated respiratory tract infection in children

Objective To explore the influence factors of recurrent respiratory tract infection(RRTIs)in children,and to provide evidence and strategies for the effective prevention and treatment of recurrent respiratory tract infection in children.Methods A total of 183 RRTIs children were selected into case group and 85 healthy children with health physical examination results were included into control group.Clinical data investigation,detection of serum trace element iron,zinc,calcium,copper,serum 25-hydroxyvitamin D[25-(OH)-D]level and mycoplasma pneumoniae(MP)-IgM antibody were performed on all the above children,and the results of the two groups were compared.The related factors of RRTIs were analyzed by multivariate Logistic regression.Results There were significant differences on the percentage of children with cesarean section,breastfeeding,eczema,allergic rhinitis,asthma,passive smoking and multiple use of antibiotics between control group and case group(P<0.05).Multivariate Logistic regression analysis showed that asthma,passive smoking and multiple use of antibiotics were risk factors for recurrent respiratory tract infections in children,and breastfeeding was a protective factor for recurrent respiratory tract infections in children.The serum levels of trace elements iron,zinc,calcium and 25-(OH)-D in case group were significantly lower than those in control group(P<0.05).The MP-IgM antibody positive rate in case group was significantly higher than that in control group(P<0.05).Conclusion It is suggested that promote positive control of childhood asthma,stay away from passive smoking,avoid abuse of antibiotics,as far as possible breastfeeding,reasonable timely supplement trace elements iron,zinc,calcium and vitamin D preparation,balanced nutrition,guard against MP infection and standardize treatment actively for preventing and controlling RRTIs.