帕瑞昔布钠预防腹腔镜胆囊切除术后咽喉痛疗效观察

目的 观察帕瑞昔布钠预防腹腔镜胆囊切除术后咽喉痛的疗效.方法 选取2018年6月至2019年1月在重庆市北碚区中医院择期行腹腔镜胆囊切除术的130例全身麻醉患者作为研究对象,性别不限,年龄21～67岁,美国麻醉医师协会分级为Ⅰ、Ⅱ级,随机分为帕瑞昔布钠组(P组)和生理盐水组(S组).手术结束前10 min P组患者静脉...

Therapeutic effect of parecoxib sodium on prevention of sore throat after laparoscopic cholecystectomy

Objective To observe the efficacy of parecoxib sodium in preventing postoperative sore throat after laparoscopic cholecystectomy.Methods A total of 130 patients with general anesthesia who underwent laparoscopic cholecystectomy from June 2018 to January 2019 in Traditional Chinese Medicine Hospital of Beibei District were selected as research objects,and the patients were gender-specific,aged 21-67 years old,American society of anesthesiologists gradeⅠ,Ⅱ,and were randomly divided into parecoxib sodium group(Group P)and saline group(Group S).Patients in group P received intravenous injection of parecoxib sodium 40 mg 10 minutes before the end of surgery,and patients in group S received an equal volum of normal saline.Visual analogue scale/score(VAS)was recorded immediately after extubation,2,6,12,and 24 hours after surgery.The adverse reactions occurred during extubation were observed and recorded.The incidence of pharyngeal complications and the use of patient controlled intravenous analgesia(PCIA)at 6 hours postoperatively,and QoR-15(15-item quality of recovery scale)scores at 24,48 hours after surgery were recorded.Results VAS scores in the group P at the moment of extubation,2,6,and 12 hours after surgery were lower than those in the group S,the number of PCIA compressions was less than that of the group S,the incidence of adverse reactions during extubation and complications in the throat at 6 hours after surgery were significantly lower than those in group S,15-item recovery quality scale scores at 24 and 48 hours after surgery were significantly higher than that in group S,and the differences were statistically significant(P<0.05).Conclusion Parecoxib sodium can effectively reduce the incidence of sore throat after laparoscopic cholecystectomy.