国内腹腔镜下子宫动脉阻断辅助子宫肌瘤挖除术临床应用的Meta分析

目的探讨腹腔镜下子宫动脉阻断辅助子宫肌瘤挖除术(LU-AO-M)对比传统单纯腹腔镜下子宫肌瘤挖除术(LM)的安全性及有效性。方法计算机检索中国知网、万方数据库、维普全文数据库、PubMed等数据库,中文文献要求为中国科学引文数据库(CSCD)来源期刊。检索建库至2015年8月LU-AO-M对比LM的试验研究,并追溯纳入文献的参考文献。由2位研究者按照纳入与排除标准独立筛选文献、提取资料并评价质量后,采用RevMan5.3软件进行Meta分析。结果共有8个研究纳入Meta分析。在术中出血、手术时间、术后肌瘤复发及月经改善情况方面,LU-AO-M组比LM组有明显优势,两组差异有统计学意义(P0.05);而在术后患者恢复情况,包括肛门排气时间、住院时间、术后病率方面,两组间差异均无统计学意义(P0.05)。结论与传统LM手术相比,LU-AO-M手术具有安全性好、复发率低、效果佳等优点,易被患者接受,可广泛推广。

A Meta analysis on the clinical application of laparoscopic uterine artery occlusion combined with myomectomy in China

Objective To evaluate the safety and effectiveness of laparoscopic uterine artery occlusion combined with myomecto‐my (LU‐AO‐M ) in treating symptomatic uterine fibroids by comparing it with traditional solely laparoscopic myomectomy (LM ) . Methods China National Knowledge Internet (CNKI) ,Wanfang data ,VIP and pubmed databases were retrieved .Chinese docu‐ments originated from the journals of Chinese Science Citation Database (CSCD) .The retrieval time was from the inception to Au‐gust 2015 .Research of experiments of LU‐AO‐M compared with LM for symptomatic uterine fibroids published from beginning of building the databases to Aug .2015 were collected ,and the reference literatures were also traced back .Two reviewers screened the literatures according to the inclusion and exclusion criteria .The useful data were extracted and the qualities were evaluated .Meta‐a‐nalysis was performed by using RevMan 5 .3 software .Results A total of 8 studies were included into Meta‐analysis .The condi‐tions of intraoperative bleeding ,operation time ,postoperative recurrence of myoma and menstrual improvement of LU‐AO‐M group were better than LM group ,and the differences had statistical significance (P<0 .05) .While the differences of the anus exhaust time ,postoperative hospital stay ,postoperative disease rate between the two groups had no statistical significance (P>0 .05) .Con‐clusion Compared with LM ,LU‐AO‐M which can be easily accepted by patients and widely promoted has many advantages ,such as higher safety ,better therapeutic effect ,lower recurrence rate .And it is is worth popularizing widely .