重庆地区278例产褥期妇女高危型HPV感染状况及对HPV认知情况调查分析

目的调查重庆地区产褥期妇女高危型人乳头状瘤病毒（HR-HPV）感染状况及对HPV的认知情况,为制定不同人群的宫颈癌筛查防治方案提供理论依据。方法采用第2代杂交捕获法（HC-2）检测技术对2011年11月至2012年6月在重庆市妇幼保健院产科门诊就诊的278例产褥期妇女进行HR-HPV检测,同时采用问卷调查的方式了解其对HPV的认知情况。结果 278例产妇中共检出HR-HPV阳性者22例,阳性率为7.91%,随着年龄的增高,人群HR-HPV阳性率有逐渐增高趋势,35岁以上产妇HR-HPV阳性率最高为12.50%（6/48）。85.25%（237/278）的妇女未接受过宫颈癌防治宣教,44.96%（125/278）的妇女对HPV完全不了解,仅20.14%（56/278）的妇女愿意主动接受HC-2检测。受教育程度高（〉12年）、高收入（〉5 000元/月）人群对HPV的认知程度相对较好,差异有统计学意义（P〈0.01）。结论产褥期妇女HR-HPV总体阳性率较低,但高龄产妇HR-HPV阳性率相对较高,极大部分产妇对HPV认知程度差,应加强宣传教育并积极与医疗服务相结合,提高妇女防癌普查意识,加强对高龄产妇的宫颈癌筛查。

Investigation on HPV infection status and cognitive degree of HPV of 278 puerperium women in Chongqing

Objective To investigate HR-HPV（high-risk human papillomavirus,HR-HPV） infection status and the cognitive degree of HPV of puerperium women in Chongqing for providing theoretical basis for the prevention and treatment of the cervical cancer.Methods The infection status of HPV in 278 outpatients of puerperium women was examined with hybrid capture Ⅱ（HC-2） in Chongqing obstetric and gynecology hospital from November 2011 to June 2012.A questionnaire survey of the cognitive degree of HPV was conducted for all the selected women.Results Among the 278 patients,22 cases were infected with HR-HPV（7.91%）.The crowd over 35 years of age was the most high rate of HR-HPV positive women（12.50%,6/48）.85.25%（237/278）of them were never accepted the examination for cervical cancer screening,and 44.96%（125/278）of them had no knowledge about HPV before.Only 20.14%（56/278）women would like to take the examination of HPV forwardly.People′s awareness level was in the crowd of higher education level（12 years）,better income（5 000 yuans per one month） was higher than that in the other groups（P0.01）.Conclusion Rarely puerperium women realized the full knowledge about HPV.To raise the screening attendance rate among appropriate women,we should teach knowledge of cervical cancer and HPV to the population especially in elder puerperium women.