| 2型糖尿病患者血清超敏C反应蛋白与糖尿病肾病相关性分析 |
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| 引用本文： | 金晓华,顾国浩,杨柄华.2型糖尿病患者血清超敏C反应蛋白与糖尿病肾病相关性分析[J].检验医学与临床,2011,8(6):655-656. |
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| 作者姓名： | 金晓华 顾国浩 杨柄华 |
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| 作者单位： | 苏州大学附属第一医院检验科,江苏苏州,215006 |
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| 摘 要： | 目的 探讨超敏C反应蛋白(hs-CRP)与糖尿病肾病(DN)发生、发展的相关性.方法 根据尿微量清蛋白(MAU)定量将90例2型糖尿病患者分为单纯糖尿病组(A组)、早期糖尿病肾病组(B组)和临床糖尿病肾病组(C组),30例本院健康体检者作为对照组,检测所有受试对象的血清hs-CRP、MAU及其他生化指标,将各组间hs-CRP值进行统计学比较,并进行相关分析.结果 糖尿病肾病各组血清hs-CRP水平均明显高于健康对照组,且hs-CRP水平随尿微量清蛋白的升高而升高.hs-CRP与三酰甘油(TG)、总胆固醇(TC)、肌酐(Cr)呈正相关.结论 hs-CRP与DN的发生相关,且随着DN进展而逐渐增高,是预测DN进展的一个重要指标.
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| 关 键 词： | 糖尿病肾病 超敏C反应蛋白 糖尿病 |
Correlation between high-sensitivity C-reactive protein and diabetic nephropathy in patients with type 2 diabetes |
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| JIN Xiao-hua,GU Guo-hao,YANG Bing-hua.Correlation between high-sensitivity C-reactive protein and diabetic nephropathy in patients with type 2 diabetes[J].Laboratory Medicine and Clinic,2011,8(6):655-656. |
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| Authors: | JIN Xiao-hua GU Guo-hao YANG Bing-hua |
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| Institution: | JIN Xiao-hua,GU Guo-hao,YANG Bing-hua(Department of Laboratory,First Affiliated Hospital,Suzhou University,Suzhou,Jiangsu 215006,China) |
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| Abstract: | Objective To investigate the relationship between serum level of high-sensitivity C-reactive protein(hs-CRP) and diabetic nephropathy(DN).Methods According to the quantitation of urinary albumin(MAU),90 patients with type 2 diabetes mellitus were divided into simple diabetes mellitus(A) group,early diabetic nephropathy(B) group and clinical diabetic nephropathy(C) group with 30 healthy examinees as controls.The level of serum hs-CRP,urinary albumin and other biochemical indicators were measured in all selec... |
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| Keywords: | diabetic nephropathy high sensitivity C-reactive protein diabete |
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