凝血及纤溶指标在弥散性血管内凝血产妇中的临床应用

目的探讨凝血及纤溶指标在弥散性血管内凝血（DIC）产妇中的临床应用价值。方法选择2009年1月至2012年8月收治的28例产科DIC产妇为观察对象，DIC患者治疗前和治疗后分别进行D-二聚体（DD）、纤维蛋白原（FIB）、活化部分凝血活酶时间（APTT）、血小板计数（PLT）的测定，并进行对比。结果28例发生DIC的产妇治疗前DD明显上升，FIB减少，APTT延长，PLT进行性下降，治疗后各指标明显改善，与治疗前比较，差异有统计学意义（P〈0．05）。结论动态检测D-D、FIB、APTT、PLT对产科DIC的诊治具有一定的意义，有助于临床诊断和监测患者预后。

Clinical application of blood coagulation and fibrinolytic indexes in parturients with DIC

Objective To investigate the clinical application value of blood coagulation and fibrinolyti＇c indexes in parturients with disseminated intravascular coagulation（DIC）. Methods 28 parturients with Dic in our hospital from January 2009 to August 2012 were selected as the observation subjects. All cases were detected D-dimer（DD）, fibrinogen（FIB） ,activated partial thromboplastin time（APTT） and platelet（PLT） count before and after treatment and the detection results were compared. Results Before treatment in 28 parturients with DIC,DD was obviously in- creased, FIB was decreased, APTT was prolonged and platelet count was progressively declined, while the various in- dexes were significantly improved after treatment,the difference between before and after treatment was statistically significant（〈0.05）. Conclusion The dynamic detection of DD,FIB,APTT and PLT has certain significance to the diagnosis and treatment of obstetric DIC and is conducive to the clinical diagnosis and the judgement of prognosis.