| 慢性肾脏病不同分期血尿酸的变化及其影响因素分析 |
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| 引用本文： | 刘迅,唐骅,彭晖,石成钢,陈珠江,娄探奇.慢性肾脏病不同分期血尿酸的变化及其影响因素分析[J].中国综合临床,2009,25(8):1048-1050. |
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| 作者姓名： | 刘迅 唐骅 彭晖 石成钢 陈珠江 娄探奇 |
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| 作者单位： | 中山大学附属第三医院肾内科,广州,510630; |
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| 摘 要： | Objective To present the baseline characteristics of serum uric acid level in patients with chro-nic kidney disease(CKD). Methods A cross-sectional study on CKD patients was carried out in our hospital for 9 months. Results 713 patients were enrolled. The top three causes of CKD in these patients were primary glomerular disease(61.2%, 436/713), essential hypertensive kidney disease (7. 2%, 51/713 ) and diabetic nephropathy (5.8% ,41/713). Serum uric acid level and the incidence of hyperuricemia were associated with the stage of CKD (F = 73. 569, P = 0. 000;χ2= 138. 156, P = 0.000). A significantly negative correlation was discovered between ser-um uric acid level and the level of glomerular filtration rate(RR = - 1. 045 ,P =0. 000). A significantly positive cor-relation of serum uric acid level was found with diastohc blood pressure, proteinuia level, smoking and BMI ( RR = 1.400,15. 149,37. 696,and 3.421 ,P <0.05 ,respectively). Conclusions The cross-sectional study of serum uric acid level in patients with CKD will help to determine the dynamic changes of serum uric acid level in Chinese CKD patients and lay a solid basis for the prevention and treatment of CKD and its complications.
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| 关 键 词： | 慢性肾脏病 血尿酸 肾小球滤过率 横断面研究 |
Cross-sectional study of serum uric acid level in patients with chronic kidney disease and its influence fac-tors |
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| Abstract: | |
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| Keywords: | Chronic kidney diseaseSerum uric acidGlomerular filtration rateCross-sectional study |
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