希舒美针剂治疗儿童肺炎支原体肺炎疗效观察

目的 观察希舒美针剂治疗肺炎支原体肺炎的临床疗效.方法 将44例肺炎支原体肺炎住院患儿分为2组,分别用希舒美针剂(阿奇霉素,辉瑞制药)和国产阿奇霉素治疗,观察比较2组的临床症状、体征的改善情况.结果 希舒美组25例,1周后治愈17例,显效2例,好转6例,有效率(有效为治愈+显效)76.00%(19/25).对照组19例,治愈5例,显效9例,好转4例,无变化1例,有效率73.68%(14/19).2组对肺炎支原体肺炎治疗均有效,2组有效率比较差异无统计学意义(x2=0.03,P>0.05).但比较2组1周治愈率(x2=7.50,P<0.05)、退热时间(t=34.05.P<0.05)和啰音消失时间(t=2.39,P<0.05),希舒美组均优于对照组,差异均有统计学意义(P均<0.05).结论 希舒美针剂治疗肺炎支原体肺炎疗效好,在改善临床症状上具有一定优越性.

Abstract：

Objective To observe the effect Azithromycin injection in the treatment of mycoplasma pneumoniae pneumonia ( MPP) in children. Methods Forty-four children of mycoplasma pneumoniae pneumonia were randomly divided into two groups, the Azithromycin group ( treat by Azithromycin, made by Pfizer) and the control group (treat by domestic Azithromycin) respectively. Improvement in symptoms and signs between the two groups were observed and compared. Results There were 25 cases in the Azithromycin group, of which,after a week, 17 cases cured,2 cases got better significantly and 6 cases got better. The effective ratio was 76. 00% ( 19/25 ). There were 19 cases in the control group, of which 5 cases cured, 9 cases got better significantly ,4 cases got better and 1 case no change. The effective ratio was 73. 68% (14/19). There was no statistical significance in the effective ratio between the two groups ( x2 = 0. 03, P > 0. 05). However, the Azithromycin group was superior to the control group both in the one week cure rate (t = 7.50,P< 0.05) and on defervescence time (t = 34. 05, P < 0. 05 ) and rales disappearance (t = 2. 39, P < 0. 05 ). Conclusion Azithromycin injection is more effective than domestic Azithromycin in the treatment of mycoplasma pneumoniae pneumonia,especially in the aspect of improving symptoms.

Effect of Azithromycin injection on mycoplasma pneumoniae pneumonia in children

Objective To observe the effect Azithromycin injection in the treatment of mycoplasma pneumoniae pneumonia ( MPP) in children. Methods Forty-four children of mycoplasma pneumoniae pneumonia were randomly divided into two groups, the Azithromycin group ( treat by Azithromycin, made by Pfizer) and the control group (treat by domestic Azithromycin) respectively. Improvement in symptoms and signs between the two groups were observed and compared. Results There were 25 cases in the Azithromycin group, of which,after a week, 17 cases cured,2 cases got better significantly and 6 cases got better. The effective ratio was 76. 00% ( 19/25 ). There were 19 cases in the control group, of which 5 cases cured, 9 cases got better significantly ,4 cases got better and 1 case no change. The effective ratio was 73. 68% (14/19). There was no statistical significance in the effective ratio between the two groups ( x2 = 0. 03, P > 0. 05). However, the Azithromycin group was superior to the control group both in the one week cure rate (t = 7.50,P< 0.05) and on defervescence time (t = 34. 05, P < 0. 05 ) and rales disappearance (t = 2. 39, P < 0. 05 ). Conclusion Azithromycin injection is more effective than domestic Azithromycin in the treatment of mycoplasma pneumoniae pneumonia,especially in the aspect of improving symptoms.