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早发型重度子痫前期的临床特点和妊娠结局分析
引用本文:魏玮,于红,沈杨,任幕兰.早发型重度子痫前期的临床特点和妊娠结局分析[J].中国综合临床,2010,26(2).
作者姓名:魏玮  于红  沈杨  任幕兰
作者单位:东南大学附属中大医院妇产科,南京,210009
摘    要:目的 探讨早发型重度子痫前期的临床特点及围产结局.方法 回顾性分析2004年11月至2009年2月东南大学附属中大医院妇产科分娩的96例重度子痫前期患者的临床资料,将其分为早发型重度子痫前期组(早发型组,妊娠<34周)和晚发型重度子痫前期组(晚发型组,妊娠≥34周).结果 与晚发型组相比,早发型组在中枢神经系统症状、蛋白尿(++)或>2 g/24 h方面、异常围生儿结局的发生率方面差异均有统计学意义(χ~2值分别为14.792、4.741、27.03,P均<0.05).早发型组围生儿的平均出生体重(1743.86±630.34)g明显低于晚发型组(2940.47±762.36)g(t=6.71,P<0.05).结论 早发型重度子痈前期患者的病情重,异常围产儿结局发生率高,存活率低.积极预防、预测、早期诊断及处理早发型重度子痛前期患者对改善母婴预后意义重大.

关 键 词:早发型重度子痫前期  并发症  围生儿结局

Clinical features and pregnancy outcomes of early-onset severe pre-eclampsia
Wei Wei,YU Hong,SHEN Yang,REN Mu-lan.Clinical features and pregnancy outcomes of early-onset severe pre-eclampsia[J].Clinical Medicine of China,2010,26(2).
Authors:Wei Wei  YU Hong  SHEN Yang  REN Mu-lan
Abstract:Objective To explore clinical features and pregnancy outcomes of early-ouset severe pre-eclampsia. Methods Clinical data of 96 cases of severe preeclampsia who deliveried in Southeast University from November 2004 to February 2009 were analyzed. The patients were divided into two groups, early-onset preeclampsia group(onset gestatioual weeks <34) and later-onset preeclampsia group(onset gestatianal weeks≥34 ). Resnits Significant difference of two groups were found in central nervous system symptom and urine protein (+ +) or > 2 g/24 h (P<0.05), incidence of abnormal prenatal outcome (χ~2=14.792,4.741,27.03 respectively;P<0.05). Mean birth weight in early-onset preeclampsia group (1743.86±630.34)g was lower than that in later-onset pre-eclampsia greup(2940.47±762.36)g (t=6.71 ,P<0.05). Conclusions Clinical symptoms of early-onset severe preeclampsia are severe , and have a higher incidence of abnormal prenatal outcomes. Prevention, prediction ,diagno-sis and management of preeclampsia are important for mothers and children.
Keywords:Early-onset severe preeclampsia  Complication  Peri-natal outcome
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