长期家庭氧疗对慢性阻塞性肺疾病患者生命质量的影响

目的：观察长期家庭氧疗（LTOT）对慢性阻塞性肺疾病（COPD）伴低氧血症患者生命质量的影响。方法：用自行编制的生命质量（QOL）评分表对32例COPD伴低氧血症患者进行生命质量评分，然后随机分为LTOT组17例和对照组15例。两组均给予常规治疗，LTOT组，氧流量0．5－2．5L/min，每日吸氧时间≥15h（包括睡眠时间），1年后分别复查QOLT分。结果：氧化组1年的QOL总均分、社会活动分、抑郁分及焦虑分和日常生活分较治疗前均明显改善（P＜0．01或＜0．05）；对照组1年后的QOL总均分、社会活动分、焦眠分恶化，P＜0．01，日常生活分及抑郁分无明显变化（P＞0．05）。结论：LTOT能改善COPD伴低氧血症患者的生命质量。

Effects of long term domiciliary oxygen therapy on the quality of life in chronic obstructive pulmonary disease

Objective:To observe the effects of long term domiciliary oxygen therapy( LTOT)on the quality of life in chronic obstructive pulmonary disease(COPD) with hypoxemia. Method:Thirty two hypoxemic patients with COPD were randomly divided into two groups (LTOT group and control group). The quality of life(QOL) score were evaluated in both groups. Both groups received regular treatment and LTOT group received oxygen therapy at a flow rate of 0.5-2.5 L/min for 15h or more every day in one year. Result:In LTOT group the total mean score of QOL, social activity score, depression score, anxiety score and general activity score were significantly improved ( P＜0.01 or＜0.05); but in the control group the total mean score of QOL, social activity score anxiety score were significantly worse, P＜0.01, general activity score and depression score did not changed. Conclusion:LTOT could improve quality of life in COPD with hypoxemia.