沙参麦冬汤对运动小鼠免疫功能的影响*

目的:探讨沙参麦冬汤对运动小鼠免疫功能的影响。方法:40只雄性昆明种小鼠，随机分为4组：安静对照组、运动对照组、运动+小剂量沙参麦冬汤组、运动+大剂量沙参麦冬汤组，运动小鼠递增负荷游泳训练40d，游泳时间由40min开始渐增至100min，第40天游泳至力竭，24h后处死取血。测定小鼠免疫器官脏器/体重比值、外周血免疫球蛋白、外周血T细胞亚群。结果：服药组小鼠脾指数、外周血IgG、IgA、CD4+T细胞百分比、CD4+/CD8+比值均显著高于运动对照组(P<0.01或P<0.05)；大剂量组小鼠胸腺指数、

The effect of Radix Ophiopogon soup on the immune function of exercises mice

Objective:To study the effect of Radix Ophiopogon soup on the immune function fo exercises mice. Method: Forty male Kunming mice were randomly divided into 4 groups: quiet control group, exercises control group, exercises + Radix Ophiopogon soup of low-dose group, exercises + Radix Ophiopogon soup of high-dose group. The exercises mice swam with progressively increased load for 40d, Twenty-four h after the last exhaustive swimming, the mice were sacrificed. The changes of immune organs/body weight ratio, the peripheral blood immunoglobulin, and peripheral blood T lymphocytes subsets of mice were determined. Result: Spleen index, peripheral blood IgG, IgA, CD4+T cells percentage and CD4+/CD8+ ratio in two drug groups were significantly higher than that in exercises group (P<0.01 or P<0.05); Hymus index, serum IgM of high-dose group were significantly higher than that in exercises group(P<0.05). Conclusion: Radix Ophiopogon soup could enhance the immunity of mice with strong endurance training.