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雷贝拉唑联合克拉霉素、阿莫西林治疗良性胃溃疡临床疗效观察
引用本文:刘桂清,程冬生,易圩生,宋金梅. 雷贝拉唑联合克拉霉素、阿莫西林治疗良性胃溃疡临床疗效观察[J]. 实用临床医学(江西), 2010, 11(10): 6-8
作者姓名:刘桂清  程冬生  易圩生  宋金梅
作者单位:刘桂清,易圩生,宋金梅(星子县社会保险医疗所内科);程冬生(星子县人民医院内科,江西,星子,332800) 
摘    要:目的观察雷贝拉唑联用克拉霉素、阿莫西林胶囊治疗良性溃疡疗效。方法 120例良性溃疡病人随机分成治疗组和对照组,治疗组采用雷贝拉唑联合克拉霉素、阿莫西林治疗;对照组采用枸橼酸铋钾联合克拉霉素、阿莫西林胶囊冶疗。结果与对照组比较治疗组腹痛缓解快(P〈0.01)。在6周后,治疗组和对照组腹痛缓解率分别是92.72%和82.14%(P〈0.05)。溃疡愈合总有效率分别是94.54%和85.71%(P〉0.05)。Hp阴转率分别是96.36%和87.5%(P〉0.05)。半年后复发率分别为3.63%和17.85%(P〈0.05)。结论治疗组治疗良性胃溃疡作用快、腹痛缓解率高、复发率低。

关 键 词:雷贝拉唑  克拉霉素  阿莫西林  联合治疗  良性溃疡  疗效观察

Clinical Curative Effect of Rabeprazole Combined with Clarithromycin and Amoxicillin Capsules on Innocent Gastrelcosis
LIU Gui-qing,CHENG Dong-sheng,YI Wei-sheng,SONG Jin-mei. Clinical Curative Effect of Rabeprazole Combined with Clarithromycin and Amoxicillin Capsules on Innocent Gastrelcosis[J]. Practical Clinical Medicine, 2010, 11(10): 6-8
Authors:LIU Gui-qing  CHENG Dong-sheng  YI Wei-sheng  SONG Jin-mei
Affiliation:1.Department of Medicines,Xingzi County Society Insurance Clinic;2.Department of Medicines,Xingzi County People's Hospital,Xingzi 332800,China)
Abstract:Objective To observe the curative effect of rabeprazole combined with clarithromycin and amoxicillin capsules on innocent gastrelcosis.Methods A total of 120 patients with innocent gastrelcosis were randomly and equally divided into treatment group and control group.The patients in treatment group were treated with rabeprazole combined with clarithromy and amoxicillin capsules,while the patients in control group were treated with bismuth potassium citrate combined with clarithromycin and amoxicillin capsules.Results Compaired with control group,the relief time of abdominal pain in treatment group was shorter than that in control group(P〈0.01).After 6 weeks,the relief rate of abdominal pain in treatment group and control group was respectively 92.72% and 82.1%(P〈0.05),the total effective rate was respectively 94.54% and 85.71%(P〈0.05),and Hp negative rate was respectively 96.36% and 87.50%(P〈0.05).After 6 months,the recurrence rate was 3.63% and 17.85%(P〈0.05),respectively.Conclusion Rabeprazole combined with clarithromycin and amoxicillin capsules can effectively treat innocent gastrelcosis with high relief rate of abdominal pain and low recurrence rate.
Keywords:rabeprszole  cluritnromycin  dmoxicinin  combination treatment  innocent gastrelcosis  curative effect
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