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血清淀粉酶及血清IgA检测在儿童腹型过敏性紫癜诊断中的价值
引用本文:皮光环,田小兵,马涛,叶飘,王媚,黄越,吴春,陈玉蓉. 血清淀粉酶及血清IgA检测在儿童腹型过敏性紫癜诊断中的价值[J]. 中国循证医学杂志, 2009, 9(9): 1031-1032
作者姓名:皮光环  田小兵  马涛  叶飘  王媚  黄越  吴春  陈玉蓉
作者单位:1. 川北医学院附院儿科,四川南充,637000
2. 川北医学院预防医学教研室,四川南充,637000
3. 四川省妇幼保健院急诊科,成都,610041
摘    要:目的探讨血清淀粉酶及血清IgA和总IgE在腹型过敏性紫癜(又称腹型紫癜)中的诊断价值。方法检测52例腹型过敏性紫癜患儿和69例无腹型过敏性紫癜患儿入院时的血清淀粉酶、血清IgA和总IgE水平,并与47例急性腹痛(胃、肠炎)组患儿进行比较。结果腹型组血清淀粉酶含量平均值为180.3±15.8IU,明显高于非腹型组和急性腹痛组(F=32.214,P=0.009);腹型组血清IgA增高病例占44.2%,与非腹型组无明显差异,但两组均高于急性腹痛组(χ^2=13.73,P=0.001);腹型组总IgE增高病例占40.4%,三组差异无统计意义(χ^2=1.80,P=0.41)。结论血清淀粉酶增高结合血清IgA增高可作为以腹痛起病的儿童过敏性紫癜诊断的参考指标,而血清总IgE意义不大。

关 键 词:腹型过敏性紫癜  血清淀粉酶  血清IgA

Clinical Significance of Serum Amylase and Serum IgA in Children Henoch Purpura Patients
PI Guang-huan,TIAN Xiao-bing,MA Tao,YE Piao,WANG Mei,HUANG Yue,WU Chun,CHEN Yu-rong. Clinical Significance of Serum Amylase and Serum IgA in Children Henoch Purpura Patients[J]. Chinese Journal of Evidence-based Medicine, 2009, 9(9): 1031-1032
Authors:PI Guang-huan  TIAN Xiao-bing  MA Tao  YE Piao  WANG Mei  HUANG Yue  WU Chun  CHEN Yu-rong
Affiliation:1. Department of Pediatrics, the Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China; 2. Department of Preventive Medicine, the Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China; 3. Emergency Department of Sichuan Provincial Hospital for Women and Children, Chengdu 610041, China)
Abstract:Objective To investigate the clinical significance of the level of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with gastrointestinal involvement(also known as "Henoch purpura ").Methods Levels of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with or without abdominal pain or patients with acute abdominal pain were compared.Results The average level(180.3 ± 15.8 IU)of serum amylase of Henoch purpura patients was significantly higher than HSP patients without abdominal pain and acute abdominal pain patients (F=32.214, P=0.O09); Ratio of cases of increased level of serum IgA in henoch purpura abdomen patients was 44.2%, and there was no significant difference with HSP patients without abdominal pain. But ratio of two groups was respectively higher than the acute abdominal pain patients group (χ^2=13.73, P=0.001); Ratio of cases of increased level of serum IgE in Henoch purpura abdomen patients accounted for 40.4%, but there was no significant difference among the three group (χ^2=l.80, P=0.41). Conclusion Levels of serum amylase increase and serum IgA increase conduce to diagnose HSP patients with the onset of abdominal pain, and serum total IgE has little significance.
Keywords:Henoch purpura  Serum amylase  Serum IgA
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