成都地区无症状高尿酸血症伴心血管危险因素的城乡流行病学调查

目的 探讨成都地区高尿酸血症患病率及合并心血管危险因素的现状及城乡差异.方法 采用随机整群抽样的方法选取成都市城市和农村社区,采用问卷、体格检查和实验室检查方式共调查35～70岁人群2 032人.结果 ①成都地区高尿酸血症患病率为17.77％,城市高于农村,分别为21.38％和14.16％.②高尿酸血症合并高胆固醇血症患者,城市高于农村,分别为34.10％和13.89％；城市女性高于农村女性,分别为39.06％和16.13％；城市男性高于农村男性,分别为26.97％和12.20％.③高尿酸血症合并高血压患者,城市高于农村,分别为58.06％和32.64％；城市女性高于农村女性,分别为59.38％和35.48％；城市男性高于农村男性,分别为56.18％和30.49％.④高尿酸血症合并糖耐量异常患者,城市女性低于农村女性,分别为28.91％和45.16％.结论 高胆固醇血症、高血压是城市高尿酸血症患者最常合并的心血管危险因素,并且明显高于农村.糖耐量异常是农村女性高尿酸血症患者最常合并的心血管危险因素.而高尿酸血症合并空腹血糖异常、高甘油三酯血症、低高密度脂蛋白血症、腹型肥胖、肥胖等心血管危险因素,城乡之间均无明显差异.

Epidemiological Study on Asymptomatic Hyperuricemia Associated with Cardiovascular Risk Factors between Urban and Rural Areas in Chengdu

Objective To investigate the prevalence of hyperuricemia and the current status as well as differences of cardiovascular risk factors in hyperuricemia patients between urban and rural areas in Chengdu.Methods We randomly sampled 2 032 patients aged from 35 to 70 years age in urban and rural communities,using a questionnaire,physical examination and laboratory tests.Results a） The prevalence of hyperuricemia was 17.77%,which was higher in urban residents（21.38%） than that in rural residents（14.16%）.b） The prevalence of hyperuricemia associated with hypercholesterolemia was higher in urban residents（34.10%） than that in rural residents（13.98%）;urban women（39.06%） were higher than rural women（16.13%） and urban men（26.97%） were higher than rural men（12.20%）.c） The prevalence of hyperuricemia associated with hypertension which was higher in urban residents（58.06%） than that in rural residents（32.64%）;urban women（59.38%） were higher than rural women（35.48%） and urban men（56.18%） were higher than rural men（30.49%）.d） The prevalence of hyperuricemia associated with impaired glucose tolerance（IGT） in urban women（28.91%） were lower than that in rural women（45.16%）.Conclusion Hypercholesterolemia and hypertension are the most commonly seen cardiovascular risk factors accompanied in patients with hyperuricemia in urban areas,which has obviously higher prevalence than in rural areas.IGT is the most commonly seen cardiovascular risk factors accompanied in patients with hyperuricemia among rural women.But in aspects of hyperuricemia associated with impaired fasting glucose（IFG）,hypertriglyceridemia,low high-density fetoprotein cholesterol,abdominal obesity and obesity,there is no difference between urban and rural areas.