超声弹性成像分级法诊断甲状腺癌的价值

目的探讨超声弹性成像分级法诊断甲状腺癌的价值。方法回顾性分析经手术病理证实的131个癌肿病灶超声弹性成像特点，并选取同期经手术病理证实的139个良性肿块的超声弹性成像作对照，比较良恶性肿块超声弹性成像评级的差异。采用ROC曲线各切点计算甲状腺结节良、恶性灵敏度和特异度，判断最佳临界值。结果恶性结节超声弹性评级以3～4级为主，而良性结节弹性评级以0～2级为主，甲状腺良、恶性肿块超声弹性成像评级差异具有统计学意义（χ2=180.44， P＜0.05）。弹性成像评级诊断甲状腺癌ROC曲线下面积0.94，诊断甲状腺癌最佳临界值为评级≥3，其灵敏度、特异度、准确率分别为93.89％、86.33%、90.00％。结论超声弹性成像技术诊断甲状腺癌具有较高临床应用价值。

Diagnostic value of sono-elastography grading in assessing thyroid carcinoma

Objective To explore the diagnostic value of sono-elastogrphic grading method in assessing thyroid carcinoma. Methods The sono-elastogrphic grading characteristics of 131 thyroid malignant masses and 139 benign thyroid masses were analyzed and compared retrospectively. According to receiver operating characteristic curve, the sensitivity and specificity of benign and malignant thyroid nodules were calculated. Thus the best threshold was determined. Results The sono-elastogrphic grading of malignant masses were 3~4 mainly while the sono-elastogrphic grading of benign thyroid masses were 0~2 mainly. There was significant difference between them （χ2=180.44, P〈0.05）. The area under the ROC of sono-elastography grading method for diagnosing the thyroid malignant masses was 0.94. The sensitivity, specificity and accuracy of sono-elastography for diagnosing thyroid malignant masses were 93.89%, 86.33%, 90.00%respectively. Conclusions The sono-elastography grading method can diagnose the thyroid carcinoma effectively.