| 人类指长比与前列腺癌关系的研究进展 |
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| 引用本文： | 孛茹婷,;杨文君,;霍正浩,;陈志强.人类指长比与前列腺癌关系的研究进展[J].中华临床医师杂志(电子版),2014(11):127-130. |
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| 作者姓名： | 孛茹婷 ;杨文君 ;霍正浩 ;陈志强 |
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| 作者单位： | [1]宁夏医科大学,银川750004; [2]生育力保持教育部重点实验室;,银川750004; [3]宁夏医科大学总医院放射科,银川750004; |
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| 基金项目： | 宁夏自然科学基金（NZl234） |
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| 摘 要： | 指长比(2D∶4D)即食指与无名指长度之比,具有性别差异,是围产期激素水平的一个重要指标。围产期激素活动会影响个体发育过程中某些心理、行为学特征及某些心血管疾病。近来2D∶4D与某些疾病患病率等之间的研究逐步成为热点。在此讨论2D∶4D与激素依赖疾病的研究,特别是2D∶4D与前列腺癌其关系的研究同样适用于其他疾病。
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| 关 键 词： | 前列腺肿瘤 雄激素类 指长比 |
Research progress .of Digit Ratio （2D-4D） and prostate cancer |
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| Institution: | Bo Ruting, Yang Wenjun, Huo Zhenghao, Chen Zhiqiang. (Ningxia Medical University, Yinchuan 750004, China) |
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| Abstract: | Digit ratio （2D ： 4D） denotes the relative length of the 2nd and 4th digits. The ratio is considered to be a proxy marker for prenatal exposure and sensitivity to sexual hormones, which can be genetically influenced. The influence of prenatal hormone exposure can reflect on psychological traits, athletic performance and diseases such as cardiovascular. Recently there has been a great deal of interest in 2D： 4D and risk of disease in adulthood. Here we briefly discussed the rationale behind the use of 2D ： 4D in studies of hormone-related diseases in later life-with particular regard to cancers of the prostate. Though the focus of this article was on prostate cancer, the rationale presented applied equally to other diseases. |
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| Keywords: | Prostatic neoplasms Androgens Digit ratio |
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