血栓弹力图在下肢深静脉血栓与肺栓塞的应用价值

目的]探讨血栓弹力图对下肢深静脉血栓形成(DVT)患者与DVT合并肺栓塞(PE)患者的应用价值.方法]选择2014年3~9月本院收治的新发DVT及DVT合并PE患者12例,其中新发DVT患者8例,DVT合并PE患者4例,选择同期无DVT或PE病史的12例健康体检者为对照组,均行下肢静脉彩超、肺动脉CT血管成像(CTA)、血栓弹力图等检查.比较DVT患者及DVT合并PE患者在血栓弹力图相关指标如凝血反应时间(R值)、凝固时间(K值)、最大血凝块强度(MA)、凝固角(Angel)、凝血综合指数(CL)的异同点.结果]DVT组、DVT合并PE组与对照组在年龄、性别、R、MA、K、Angel、CL方面比较,组间比较差异无统计学意义(P>0.05).结论]下肢深静脉血栓形成与下肢深静脉血栓形成合并肺栓塞在血栓弹力图指标上无明显差异,血栓弹力图在VTE中的应用价值尚需进一步研究.

Clinical Value of Thrombelastogram on Patients of Deep Venous Thrombosis and Pulmonary Em-bolism

Objective]To investigate the clinical value of thrombelastogram on patients of deep venous throm-bosis (DVT)and DVT combined with pulmonary embolism (PE).Methods]12 cases of DVT and DVT with PE in the hospital from March 2014 to September 2014 were selected,of which 8 cases were newly diagnosed as DVT patients,and 4 cases as DVT combined with PE.12 healthy subjects with no history of DVT nor PE were selected as control group,who underwent venous ultrasonography,CT pulmonary angiography (CTA)and Thrombelasto-gram examination.Thrombelastogram index related with DVT and DVT with PE such as blood coagulation time (R),coagulation time (K),maximum blood clot strength (MA),angle,blood coagulation indicators were com-pared with.Results]There was no statistical significant difference between the DVT group,the DVT combined with PE group and the control group in age,gender,R,MA,K,Angel and CL (P >0.05).Conclusion]Deep venous thrombosis and deep venous thrombosis combined with pulmonary embolism had no obvious difference in the Thrombelastogram index ,the application value of Thrombelastogram in VTE needs to be further studied.