| 妊娠相关血浆蛋白-A、缺血修饰白蛋白在急性冠脉综合征早期诊断中的价值 |
| |
| 引用本文： | 李方雄,卢桂静,漆红,余再新,吴声滨,宁阳根.妊娠相关血浆蛋白-A、缺血修饰白蛋白在急性冠脉综合征早期诊断中的价值[J].医学临床研究,2008,25(10):1815-1817. |
| |
| 作者姓名： | 李方雄 卢桂静 漆红 余再新 吴声滨 宁阳根 |
| |
| 作者单位： | 中南大学湘雅医院心内科,湖南,长沙,410008 |
| |
| 摘 要： | 目的]探讨妊娠相关血浆蛋白-A(PAPP-A)及缺血修饰白蛋白(IMA)在急性冠脉综合征(ACS)早期诊断中的意义.方法]87例疑似ACS患者在胸痛发作3h内采取静脉血测定PAPP-A、IMA及相关指标并进行分析.经冠状动脉造影证实冠脉正常者作为对照组27例,稳定性心绞痛(SAP)组20倒,ACS组40例,包括不稳定性心绞痛(UAP)23例、急性心肌梗死(AMI)17例.结果]①ACS组中PAPP-A及IMA含量(16.19±2.13 mIU/L,0.608±0.097ABSU)明显高于SAP组(4.720±1.960 mIU/L,0.436±0.022 ABSU)及对照组(4.390±1.150 mIU/L,0.246±0.135 ABSU)(P<0.001),IMA与PAPP-A呈显著正相关(r=0.80,P<0.01).②PAPP-A及IMA对检测ACS早期的灵敏度分别为85%及80%,两者联合灵敏度达95%.结论]PAPP-A及IMA在外周血中明显升高,可能是ACS早期的预测因子,两者联合检测可提高对ACS早期诊断能力.
|
| 关 键 词： | 冠状动脉疾病/诊断 急性病 妊娠相关a血浆蛋白质/分析 血清白蛋白/分析 |
Predictive Role of Pregnancy-associated Plasma Protein-A and Ischemia-Modified Albumin in Early Diagnosis of Acute Coronary Syndrome |
| |
| LI Fang-xiong,LU Gui-jin,QI Hong,et al.Predictive Role of Pregnancy-associated Plasma Protein-A and Ischemia-Modified Albumin in Early Diagnosis of Acute Coronary Syndrome[J].Journal of Clinical Research,2008,25(10):1815-1817. |
| |
| Authors: | LI Fang-xiong LU Gui-jin QI Hong |
| |
| Institution: | LI Fang-xiong,LU Gui-jin,QI Hong,et al(Department of Cardiology,Xiangya Hospital,Central South University,Changsha 410008,China) |
| |
| Abstract: | Objective]To explore the significance of pregnancy-associated plasma protein-A(PAPP-A) and ischemia-modified albumin(IMA)in the early diagnosis of acute coronary syndrome(ACS).Methods]Eighty-seven patients with acute chest pain within 3 hours were included in the study.Values of PAPP-A,IMA and cardiac troponin I(cTnI) were tested and analyzed.Electrocardiogram(ECG) was recorded in patients.Twenty-seven controls with normal coronary angiography and 20 patients with stable angina,40 patients with ACS includ... |
| |
| Keywords: | coronary disease/DI acute disease pregnancy-associated alpha-plasma protein/AN serum albumin/AN |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
