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子宫内膜异位症生育指数对子宫内膜异位症合并不孕患者远期妊娠率的预测价值
引用本文:郭一卜,黄向红.子宫内膜异位症生育指数对子宫内膜异位症合并不孕患者远期妊娠率的预测价值[J].医学临床研究,2021(2).
作者姓名:郭一卜  黄向红
作者单位:中国人民解放军第九八六医院北区妇产科;中国人民解放军第九八六医院妇产科
摘    要:【目的】探讨子宫内膜异位症生育指数(EFI)对子宫内膜异位症(EMT)合并不孕患者远期妊娠率的预测价值。【方法】选取2017年1月至2020年1月在本院接受腹腔镜手术治疗200例的EMT合并不孕患者,根据治疗前EFI将患者分为A组(n=85,≥9分)、B组(n=48,5?8分)、C组(n=42,≤4分),随访3年统计三组患者妊娠情况,分析EH对患者3年妊娠率的预测价值。【结果】三组年龄、不孕年限、不孕比例、妊娠率、足月分娩率、术后首次妊娠时间比较差异有统计学意义(P<0.05)。C组妊娠率、足月分娩率显著低于A组、B组,术后首次妊娠时间长于A组、B组,其差异有统计学意义(P<0.05);B组术后首次妊娠时间长于A组,差异有统计学意义(P<0.05)。三组术后6个月妊娘率均显著高于13?24个月、25?36个月;A组术后6个月妊娠率高于C组(P<0.05),但C组13?24个月、25?36个月妊娠率高于A组(P<0.05)。ROC曲线显示:EFI预测术后妊娠率的曲线下面积为0.76,特异度为62.3%,灵敏度为79.8%。【结论】EFI≥9分的EMT合并不孕患者3年妊娠率较高,术后首次妊娠时间较短,EFI对预测EMT合并不孕患者术后妊娠具有重要价值。

关 键 词:子宫内膜异位症/并发症  不育  女(雌)性  妊娠率  生育力  预测

Predictive Value of Endometriosis Fertility Index on Long-term Pregnancy Rate in Patients with Endometriosis Combined with Infertility
GUO Yi-bu,HUANG Xiang hong.Predictive Value of Endometriosis Fertility Index on Long-term Pregnancy Rate in Patients with Endometriosis Combined with Infertility[J].Journal of Clinical Research,2021(2).
Authors:GUO Yi-bu  HUANG Xiang hong
Institution:(Deparment of Obstetrics and Gymecology,North District,The 986th Hospital of Chinese People's Liberation Army,Xi'an Shaanxi,710054)
Abstract:Objective]To investigate the predictive value of endometriosis frilitiy index(EFI) on the long term pregnaney rate in patients with endometriosis combined with inferility.Methods]A total of 200 patients with endo.metriosis and infertility who underwent laparoscopic surgery in our hospital from January 2017 to January 2020 were selected.The patients were fllowed up to observe the 3-year pregnancy rate after laparoscopic surgery.A total of 25 patients(12.5%)were lost to fllw up.According to the EFI before treatment,patients were divided into 3 groups:A group(85 cases,EFI≥9 points),B group(48 cases,5-8 points),C group(42 cases,≤4 points).The preg-nancy status in the 3 groups of patients were comparcp and the predictive value of EFI in patients'3 year pregnancy rates were evaluated.Results]There were stistically signifiant diflerences in age,inferility years,proporion of inferility,pregnancy rate,full term delivery rate,and time of first prcgnancy after operation in the three groups(P<0.05).The pregnancy rate and fll term delivery rate in the C group were lower than those in the A group and B group,and the differences were stistitally signifiant(P<0.05).The first pregnancy time after surgery in the C group was longer than that in the A group and B group,and the difference was saitically significant(P<0.05).The first pregnancy time after surgery in the B group was longer than that in the A group,and the difference was statistically significant(P<0.05).The difference in pregnancy rates between 6.13-24,and 25-36 months in the three groups was statistically significant(P<0.05).The pregnancy rate within 6 months after surgery in the A group was higher than that in the C group(P<0.05),while the pregnancy rate in 13-24 and 25-36 months of the C group was higher than that of the A group(P<0.05).The ROC curve showed that the area under the curve for pre-dicting the postoperative pregnancy rate by EFI was 0.76(P<0.05),the specificity was 62.3%,and the sensitivity was 79.8%.Conclusion]The 3-year pregnancy rate is higher in patients with endometriosis and iferility(EF1≥9 points),and the first pregnancy time is shorter after surgery.EFI has certain value in predicting postoperative preg-nancy.It can be used for early evaluation of patients'pregnancy.According to EFI,strict management and treatment plan can be adjusted to improve the long term pregnancy rate.
Keywords:Endometriosis/CO  Ineriliy  Female  Pregnaney Rate  Ferilit  Forecasting
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