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广西仫佬族HLA-A、B、C、DR和DQ抗原的分布
引用本文:孙水仙,周微雅,米新玉,陆胜经,裴冀,黄普华.广西仫佬族HLA-A、B、C、DR和DQ抗原的分布[J].中国输血杂志,1988(2).
作者姓名:孙水仙  周微雅  米新玉  陆胜经  裴冀  黄普华
作者单位:中国医学科学院输血所,广西壮族自治区人民医院,中国医学科学院输血所,广西壮族自治区人民医院,中国医学科学院输血所,广西壮族自治区人民医院
摘    要:本文对100名仫佬族人做了HLA-A、B、C、DR和DQ分型。仫佬族人的HLA IⅠ抗原的分布趋势与南方人群和广西汉、壮、苗、瑶各族基本一致。例如:A位点频率较高的抗原有A2、A9和A11;B位点频率较高的有B40、B13、Bw46等。C位点频率较高的有Cw3、Cw1(含CX46)和Cw7。仫佬族较为特殊的是B17抗原频率低于南方人群。仫佬族HLAⅡ类抗原DR、DQ的分布与广西壮族比较,差别似乎较大。这是否由于民族的起源不同,或是其它因素造成,有待进一步研究。


Distribution of HLA-A,B,C,DR and DQ Antigens in Mulao Nationality in Guangxi Area
Abstract:One hundred unrelated healthy indi- viduals of the Mulao nationality were ty- ped for HLA-A, -B, -C, -DR and -DQ locus antigens. The distribution of HLA class I antigens is similar to that of Zhu- ang, Miao and Yao nationalities in the Guangxi Area and to that of the Han po- pulations in southern China. For example, A2, A9 and A11 are much more frequent in A locus, as well as B40, B13 and Bw46 in B locus and Cw3. Cw1 (including Cx46) and Cw7 in C locus. The antigen B17 sho- wing a lower frequency in Mulao natio- nality than in other populations in sou- thern China is quite especial. The distri- bution of DR and DQ antigens in HLA class II shows still more different between Mulao and Zhuang nationalities. It is not clear whether the origin of the two na- tionalities or other factors give rise to their difference, and it needs further study.
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