| 急性冠状动脉综合征患者治疗前后血清高敏C反应蛋白的变化 |
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| 引用本文： | 方玉才,邢小中,蒋洪平,黄水明,钱健.急性冠状动脉综合征患者治疗前后血清高敏C反应蛋白的变化[J].上海医学检验杂志,2005(5). |
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| 作者姓名： | 方玉才 邢小中 蒋洪平 黄水明 钱健 |
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| 作者单位： | 桐庐县第一人民医院检验科 浙江桐庐311500
(方玉才，邢小中，蒋洪平)，桐庐县第一人民医院心内科 浙江桐庐311500
(黄水明)，桐庐县第一人民医院心内科 浙江桐庐311500(钱健) |
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| 摘 要： | 目的研究急性冠状动脉综合征(ACS)患者住院治疗前后血清高敏C反应蛋白(hs-CRP)含量的变化及意义。方法采用胶乳增强免疫透射比浊法测定137例ACS患者、52例稳定型心绞痛(SAP)患者、86名健康人血清中hs-CRP的含量。结果SAP、ACS患者hs-CRP水平与正常对照组相比均明显增高。ACS患者住院治疗后血清hs-CRP浓度均明显降低。入院时hs-CRP>10.0mg/L提示再发冠状动脉病变的可能性很大,出院时hs-CRP>3.0mg/L的患者易再发心绞痛、心肌梗死。结论血清hs-CRP在ACS发生时明显增高,可以作为ACS的预报,是一个独立的心血管疾病危险因素。
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| 关 键 词： | 高敏C反应蛋白 急性冠状动脉综合征 稳定型心绞痛 |
Changes of serum high-sensitivity C-reactive protein in patients with acute coronary syndrome before and after treatment |
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| Abstract: | Objective To study the change and significance of serum high-sensitivity C-reactive protein (hs-CRP) in patients with acute coronary syndrome(ACS) before and after treatment. Methods The serum levels of hs-CRP in 137 patients with ACS, 52 patients with stable aragina pectoris (SAP) and 86 normal controls were determined by emul enhanced immunoturbidimetric assay. Results The level of hs-CRP in ACS group and SAP group was significantly higher than that in control group(P<0.01). The level of hs-CRP in ACS patients was significantly decreased after treatment (P<0.01). Patients with hs-CRP>10.0 mg/L during hospitalization or with hs-CRP>3.0 mg/L on leaving hospital were more possible to occurence of palindromia. Conclusions The level of hs-CRP was significantly high in ACS. It could be predicted occurrence of ACS. The hs-CRP is a indepedent risk factor of ACS. |
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| Keywords: | High-sensitivity C-reactive protein Acute coronary syndrome Stable anagina pectoris |
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