气单胞菌研究概况

气单胞菌在自然界分布广泛，除引发鱼类疫病外也可导致人体不同部位的感染，东南亚国家是腹泻病相对高发的地区，对肝胆外科术后病例有较高的机会性感染和疾病负担；全球耐药特征呈上升趋势，多重耐药（MDR）和超广谱-内酰胺酶（ESBLs）菌株与水产养殖业的抗生素过度使用后环境污染有关；不同地域气单胞菌的毒力因子存在差异。有关部门应制定措施控制水源、食品与养殖环境，降低肠道和非肠道感染的疾病负担。

Progress in research of Aeromonas

Aeromonas is wildly distributed in nature. In addition to causing diseases in fishes, it can also lead to multi-site infections in humans. Southeast Asia is the most affected region, and the opportunistic infection rate is high and the disease burden is heavy in patients receiving hepatobiliary surgery. The antibiotic resistance of Aeromonas is increasing globally. The emerging of multidrug-resistant (MDR) and extended-spectrum -lactamases (ESBLs) strains is related to the environment pollution due to the overuse of antibiotic in aquaculture. The distribution of virulent genes varied with Aeromonas species and regions. It is necessary to develop related food, water source and breeding environment control measures to reduce the disease burden caused by intestinal and non-intestinal infections.