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| 中、晚孕期超声筛查胎儿染色体异常 | |
| 引用本文： | 潘玉萍,蔡爱露,解丽梅,王冰,王丽芝,王岳平,赵一理.中、晚孕期超声筛查胎儿染色体异常[J].中国医学影像技术,2010,26(8):1507-1510. |
| 作者姓名： | 潘玉萍 蔡爱露 解丽梅 王冰 王丽芝 王岳平 赵一理 |
| 作者单位： | 1. 中国医科大学附属盛京医院超声科,辽宁,沈阳,110004 2. 中国医科大学附属盛京医院妇产科,辽宁,沈阳,110004 3. 中国医科大学附属盛京医院遗传室,辽宁,沈阳,110004 |
| 摘 要： | 目的 探讨中、晚孕期超声筛查胎儿染色体异常的价值.方法 在妊娠中期和晚期,分别对有产前诊断指征的2955名和173名孕妇行羊水和脐血穿刺术检查染色体核型,比较不同指征孕妇的异常核型检出率,并分析染色体异常与超声异常的关系.结果 接受羊水穿刺的2955名孕妇中,异常核型150名,异常率5.08%;超声异常91名,异常核型11名,异常率12.09%;超声异常组染色体异常检出率(12.09%)明显高于唐氏高危组(4.46%)、高龄孕妇组(3.89%)、不良孕产史组(2.74%)(P＜0.05).173名脐血染色体核型分析中,26名为异常核型,异常率15.03%;超声异常118名,异常核型16名,异常率13.56%.结论 中、晚孕期超声筛查胎儿染色体异常有很大价值. |
| 关 键 词： | 羊膜腔穿刺术 脐带穿刺术 核型分析 超声检查 产前 染色体异常 |
| 收稿时间： | 4/7/2010 12:00:00 AM |
| 修稿时间： | 2010/4/30 0:00:00 |
Ultrasonography screening for fetal chromosomal abnormalities during the second and third trimesters of gestation |
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| PAN Yu-ping,CAI Ai-lu,XIE Li-mei,WANG Bing,WANG Li-zhi,WANG Yue-ping and ZHAO Yi-li.Ultrasonography screening for fetal chromosomal abnormalities during the second and third trimesters of gestation[J].Chinese Journal of Medical Imaging Technology,2010,26(8):1507-1510. | |
| Authors: | PAN Yu-ping CAI Ai-lu XIE Li-mei WANG Bing WANG Li-zhi WANG Yue-ping and ZHAO Yi-li |
| Institution: | Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Obstetrics & Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Heredity, Shengjing Hospital of China Medical University, Shenyang 110004, China;Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China |
| Abstract: | |
| Keywords: | Amniocentesis Cordocentesis Karyotyping Ultrasonography prenatal Chromosomal abnormality |
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