超声诊断非酒精性脂肪肝与CT定量测量腹部脂肪分布的相关性

目的 观察健康人群超声诊断非酒精性脂肪肝（NAFL）与CT定量测量腹部脂肪分布的相关性。方法 分析1 285名体检者一般资料、血糖、生化指标和超声脂肪肝诊断结果以及CT定量测量腹部脂肪面积值，包括总脂肪（TF）、内脏脂肪（VF）和皮下脂肪（SF），观察超声诊断NAFL与CT定量测量值的关系。结果 最终诊断NAFL 504例。超声诊断NAFL与非脂肪肝在脐层面和L2/3层面VFA、SFA、TFA之间差异均有统计学意义（P均<0.05）。男性脐层面VFA、L2/3层面VFA及SFA越高，NAFL发生风险率越高；女性L2/3层面VFA及SFA越高，NAFL发生风险率越高。超声诊断NAFL与脐层面及L2/3层面脂肪面积均呈较好的正相关，且L2/3层面VFA、SFA及TFA均高于脐层面。结论 健康成人中NAFL与腹部脂肪含量相关；VF异常积累易致非肥胖人群罹患NAFL。

Correlation between ultrasonic diagnosis of non-alcoholic fatty liver and CT quantitative measurement of abdominal fat distribution

Objective To investigate the correlation between ultrasonic diagnosis of non-alcoholic fatty liver (NAFL) and CT quantitative measurement of abdominal fat distribution in healthy people. Methods The general information, blood glucose, biochemical indexes, ultrasonic diagnosis and CT quantitative measurement of abdominal fat of 1 285 subjects who underwent regular physical examination were analyzed. Abdominal fat included total fat (TF), visceral fat (VF) and subcutaneous fat (SF). The relationships between ultrasound diagnosis of NAFL and CT measurements were explored. Results NAFL was diagnosed in 504 cases. There were significant differences of VFA, SFA and TFA between NAFL and non-fatty liver diagnosed with ultrasound (all P<0.05). For men, the higher the VFA at navel level,VFA and SFA at L2/3 levels, the higher the risk of NAFL, while for women, the higher the VFA and SFA at L2/3 levels, the higher the risk of NAFL. The positive correlation between ultrasonic diagnosis of NAFL and fat area of the navel and L2/3 levels, VFA, SFA and TFA at L2/3 levels were higher than those at the navel levels. Conclusion There was certain relationship between NAFL and abdominal fat content in healthy adults, especially abnormal accumulation of visceral fat, which was more likely to lead NAFL in non-obese subjects.