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18F-FDG PET/CT在乳腺外Paget病分期及随访中的应用(附11例报道)
引用本文:范岩,张建华,付占立,张旭初,崔永刚,王彦福,白艳霞,王荣福.18F-FDG PET/CT在乳腺外Paget病分期及随访中的应用(附11例报道)[J].中国医学影像技术,2015,31(12):1898-1901.
作者姓名:范岩  张建华  付占立  张旭初  崔永刚  王彦福  白艳霞  王荣福
作者单位:北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034,北京大学第一医院核医学科, 北京 100034
摘    要:目的 探讨18F-FDG PET/CT在乳腺外Paget病的分期及治疗后随访中的临床应用价值。方法 回顾性分析11例经手术或活检病理证实的乳腺外Paget病患者临床及影像学检查资料。结果 11例患者中,7例术前接受18F-FDG PET/CT检查,4例术后接受18F-FDG PET/CT检查。10例检查时存在皮肤病变,1例无皮肤病变;9例病灶位于阴囊,2例病灶位于腋窝。皮肤病灶18F-FDG PET/CT均表现为轻、中度摄取增高。5例患者伴有腹股沟淋巴结转移(5/11,45.45%)。2例既往有其他恶性肿瘤病史的患者均未见肿瘤复发征象;1例阴囊Paget病手术切除后1年局部复发患者,18F-FDG PET/CT发现升结肠肿物,伴肝脏、骨骼及淋巴结多发转移。结论 18F-FDG PET/CT有助于乳腺外Paget病的术前分期,并可用于临床随访。

关 键 词:皮肤肿瘤  正电子发射型体层摄影术  体层摄影术  X线计算机  氟脱氧葡萄糖  分期
收稿时间:2015/2/21 0:00:00
修稿时间:2015/11/2 0:00:00

Application of 18F-FDG PET/CT in staging and follow-up of extramammary Paget's disease: Report of 11 cases
FAN Yan,ZHANG Jian-hu,FU Zhan-li,ZHANG Xu-chu,CUI Yong-gang,WANG Yan-fu,BAI Yan-xia and WANG Rong-fu.Application of 18F-FDG PET/CT in staging and follow-up of extramammary Paget''s disease: Report of 11 cases[J].Chinese Journal of Medical Imaging Technology,2015,31(12):1898-1901.
Authors:FAN Yan  ZHANG Jian-hu  FU Zhan-li  ZHANG Xu-chu  CUI Yong-gang  WANG Yan-fu  BAI Yan-xia and WANG Rong-fu
Institution:Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China,Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China and Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China
Abstract:Objective To investigate the value of 18F-FDG PET/CT in staging and follow-up of patients with extramammary Paget's disease. Methods Clinical and imaging data of 11 patients with extramammary Paget's disease who underwent whole-body 18F-FDG PET/CT were retrospectively analyzed. All the lesions were confirmed pathologically by operation or biopsy. Results Of all the 11 patients, 7 cases underwent 18F-FDG PET/CT scanning before operation, while the other 4 cases underwent 18F-FDG PET/CT after operation. There were 10 skin involved cases and 1 case without skin lesion. The primary lesions located at scrotum in 9 cases and located at axillary region in the other 2 cases. All the skin lesions showed light to mild increased FDG uptake. Totally 5 cases combined with inguinal lymph nodes metastasis (5/11,45.5%). No recurrence was found in 2 cases with other previously primary malignant tumors. There was a patient with local recurrence in scrotum, and coexisted colon cancer with multiple metastasis including liver, bones and lymph nodes were found by 18F-FDG PET/CT. Conclusion 18F-FDG PET/CT is very useful for the staging and follow-up of extramammary Paget's disease.
Keywords:Dermatoma  Positron-emission tomography  Tomography  X-ray computed  Fluorodeoxyglucose  Staging
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