| 18F-FDG PET/CT诊断原发性肝癌和肝转移瘤的价值 |
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| 引用本文： | 王洋洋,王振光,李大成,武凤玉,刘思敏,薛伟.18F-FDG PET/CT诊断原发性肝癌和肝转移瘤的价值[J].中国医学影像技术,2015,31(1):77-81. |
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| 作者姓名： | 王洋洋 王振光 李大成 武凤玉 刘思敏 薛伟 |
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| 作者单位： | 青岛大学附属医院PET/CT中心, 山东 青岛 266100;青岛大学附属医院PET/CT中心, 山东 青岛 266100;青岛大学附属医院PET/CT中心, 山东 青岛 266100;青岛大学附属医院PET/CT中心, 山东 青岛 266100;青岛大学附属医院PET/CT中心, 山东 青岛 266100;青岛大学附属医院PET/CT中心, 山东 青岛 266100 |
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| 摘 要： | 目的 探讨18F-FDG PET/CT在原发性肝癌和肝转移瘤诊断中的应用价值。方法 回顾性分析108例肝脏肿瘤患者临床资料、常规影像(超声、增强CT和MRI)及PET/CT资料,病灶18F-FDG浓集水平高于周围正常肝组织为诊断恶性标准。结果 108例肝脏肿瘤各种影像检查共检出194个病灶,70个肝细胞癌病灶18F-FDG PET/CT发现34个,最大标准摄取值(SUVmax)为4.95±3.86;23个胆管细胞癌病灶PET/CT发现22个,SUVmax为7.65±3.88;101个肝内转移瘤病灶PET/CT发现97个,SUVmax为9.65±5.34。18F-FDG PET/CT对肝转移瘤和胆管细胞癌的阳性检出率(96.04%和95.65%)均高于肝细胞癌(48.57%),差异均有统计学意义(P均<0.05);肝转移瘤与肝细胞癌、胆管细胞癌与肝细胞癌之间SUVmax的差异均有统计学意义(P均<0.05)。不同原发肿瘤来源的肝转移灶的SUVmax值差异无统计学意义(F=2.07,P>0.05)。结论 18F-FDG PET/CT对原发性肝癌和肝转移瘤的病灶检出率不同,病灶的SUVmax值亦存在差异;在肝脏肿瘤诊断与分期时需科学合理应用18F-FDG PET/CT。
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| 关 键 词： | 肝肿瘤 肿瘤转移 正电子发射型体层摄影术 体层摄影术 X线计算机 18F氟脱氧葡萄糖 |
| 收稿时间： | 2014/7/22 0:00:00 |
| 修稿时间： | 2014/10/23 0:00:00 |
Value of 18F-FDG PET/CT in diagnosis of primary hepatocellular carcinoma and liver metastases |
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| WANG Yang-yang,WANG Zhen-guang,LI Da-cheng,WU Feng-yu,LIU Si-min and XUE Wei.Value of 18F-FDG PET/CT in diagnosis of primary hepatocellular carcinoma and liver metastases[J].Chinese Journal of Medical Imaging Technology,2015,31(1):77-81. |
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| Authors: | WANG Yang-yang WANG Zhen-guang LI Da-cheng WU Feng-yu LIU Si-min and XUE Wei |
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| Institution: | PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China;PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China;PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China;PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China;PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China;PET/CT Center, the Affiliated Hospital of Qingdao University, Qingdao 266100, China |
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| Abstract: | Objective To explore the application value of 18F-FDG PET/CT in diagnosis of primary hepatocellular carcinoma and liver metastases. Methods The clinical results and imaging findings including ultrasound, enhancement CT, MRI and PET/CT of 108 patients with liver neoplasms were retrospectively analyzed. The malignant lesion was diagnosed when 18F-FDG foci concentration level with the tumor was higher than the surrounding normal liver tissue. Results In 108 cases, a total of 194 lesions were detected by common imaging and PET/CT. Amongst 70 hepatocellular carcinomas (HCC), 18F-FDG PET/CT revealed 34 lesions, with the maximum standardized uptake value (SUVmax) was 4.95±3.86. 18F-FDG PET/CT also revealed 22 of 23 cholangiocellular carcinomas (CCC), with the SUVmax of 7.65±3.88. And 97 cases of 101 liver metastatic lesions, with the SUVmax of 9.65±5.34. The positive finding of live metastases and CCC undergoing 18F-FDG PET/CT (detection rates 96.04% and 95.65%) were higher than that of HCC (48.57%, both P<0.05). The SUVmax between liver metastases and HCC, CCC and HCC were significantly different (both P<0.05), in addition, there was no significant difference among liver metastases derived from different primary tumors (F=2.07, P>0.05). Conclusion 18F-FDG PET/CT have different accuracies for detecting primary liver neoplasms and liver metastases, which are also with different SUVmax, it is necessary to be scientific and rational use of 18F-FDG PET/CT in the diagnosis and staging of liver neoplasms. |
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| Keywords: | Liver neoplasms Neoplasm metastasis Positron-emission tomography Tomography X-ray computed Fluorodeoxyglucose F18 |
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