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实时组织弹性成像诊断肝纤维化
引用本文:裴书芳,丛淑珍,冯占武,甘科红,周立峰,李康.实时组织弹性成像诊断肝纤维化[J].中国医学影像技术,2010,26(5):893-895.
作者姓名:裴书芳  丛淑珍  冯占武  甘科红  周立峰  李康
作者单位:广东省人民医院超声医学科,广东省医学科学院,广东,广州,510080
摘    要:目的 评价实时组织弹性成像(RTE)在诊断肝纤维化中的价值.方法 应用RTE对70例慢性乙型病毒性肝炎(乙肝)患者的肝脏纤维化程度进行评分,分为0~4分,0分为阴性,1~4为阳性,并与肝组织纤维化病理学分期进行对照.结果 RTE评为阳性者52例,评为阴性者18例,RTE诊断肝纤维化的敏感度、特异度、准确率分别为97.73%(43/44),65.38%(17/26)和85.71%(60/70).以RTE阳性作为肝纤维化的诊断标准,通过ROC曲线分析弹性图像硬度评分的曲线下面积为0.92.结论 RTE为诊断肝纤维化提供了新的手段,是一项具有发展前景的新的无创性的诊断方法.

关 键 词:肝硬化  弹性成像技术
收稿时间:2009/9/18 0:00:00
修稿时间:2009/10/22 0:00:00

Real-time tissue elastographic evaluation of liver fibrosis
PEI Shu-fang,CONG Shu-zhen,FENG Zhan-wu,GAN Ke-hong,ZHOU Li-feng and LI Kang.Real-time tissue elastographic evaluation of liver fibrosis[J].Chinese Journal of Medical Imaging Technology,2010,26(5):893-895.
Authors:PEI Shu-fang  CONG Shu-zhen  FENG Zhan-wu  GAN Ke-hong  ZHOU Li-feng and LI Kang
Institution:Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;Department of Ultrasound, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
Abstract:Objective To observe the value of real-time tissue elastography (RTE) in diagnosing liver fibrosis. Methods RTE was performed in 70 patients with chronic hepatitis B to classify them into five groups ( scores 0-4, 0: negative, 1-4 : positive). The elastogram were compared with the fingdings of pathology. Results Fifty-two patients were RTE positive, 18 were RTE negative. The sensitivity, specificity and the accuracy rate of RTE for diagnosing liver fibrosis was 97.73% (43/44), 65.38% (17/26), 85.71% (60/70), respectively. Taking RTE positive as the diagnosis standard of liver fibrosis, the area under the curve of ROC was 0.92 . Conclusion RTE is a new and promising sonography-based noninvasive method for the assessment of liver fibrosis in patients with chronic hepatitis B.
Keywords:Liver cirrhosis  Elasticity imaging techniques
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