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肝脏影像的薄板样条弹性配准
引用本文:谢耀钦,包尚联,陈国跃.肝脏影像的薄板样条弹性配准[J].中国医学影像技术,2009,25(3):499-503.
作者姓名:谢耀钦  包尚联  陈国跃
作者单位:1. 北京大学医学物理和工程北京市重点实验室,北京,100871
2. 秋田县立大学电子情报学系,日本秋田县,本庄,015-0055
基金项目:国家自然科学基金,北京市自然科学基金,北京教委共建项目 
摘    要:目的 在弹性配准中考虑肝脏周边解剖结构间运动的不连续性.方法 采用双薄板样条弹性配准方法,利用制定治疗计划过程中于参考影像中勾画的轮廓线信息对特征点进行分区.结果 对临床病例进行配准,沿人体上下方向偏移量绝对值的平均误差从配准前的11.25 mm降到配准后的1.80 mm,标准方差从2.60 mm降到1.39 mm.结论 该方法考虑了脏器间运动的不同模式,并且不需要在配准中对目标影像进行轮廓线勾画.

关 键 词:动态适形调强放疗  影像导引的放射治疗  弹性配准  薄板样条
收稿时间:2008/11/27 0:00:00
修稿时间:2008/12/23 0:00:00

Thin plate spline deformable registration of liver images
XIE Yao-qin,BAO Shang-lian and CHEN Guo-yue.Thin plate spline deformable registration of liver images[J].Chinese Journal of Medical Imaging Technology,2009,25(3):499-503.
Authors:XIE Yao-qin  BAO Shang-lian and CHEN Guo-yue
Institution:Beijing City Key Lab of Medical Physics & Engineering, Peking University, Beijing 100871, China;Beijing City Key Lab of Medical Physics & Engineering, Peking University, Beijing 100871, China;Department of Electronics and Information System, Akita Prefectural University, Honjyo Akita 015-0055, Japan
Abstract:Objective To take the discontinuous movements of anatomic structures around liver into account in deformable registration. Methods Bi-TPS (thin plate spline) deformable registration was proposed. The method partitioned the feature points according to the physician's segmentation of the template image during treatment planning. Results The average error and the standard deviation (SD) in modeling the absolute value of the displacement in the superior/inferior direction were reduced from (11.25±2.60)mm before registration to (1.80±1.39)mm after registration in a patient with liver tumor. Conclusion The proposed method can take the different motions of anatomic structures into consideration and allow segmented registration without delineating contours in the target images.
Keywords:Four dimensional intensity modulated radiation therapy  Image-guided radiation therapy  Deformable registration  Thin plate spline
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