血脂水平与视网膜静脉阻塞关系的临床观察

目的研究视网膜静脉阻塞（RV0）患者血脂水平的变化，以探讨血脂升高是否是RV0的独立危险因素，为治疗和预防该病提供客观依据。方法采用病例对照研究，收集40例确诊为RVO且未接受过药物治疗的患者作为病例组（其中视网膜中央静脉阻塞（CRVO）患者28人，视网膜分支静脉阻塞（BRV0）患者12人），同期健康体检且既往无眼底血管性疾病病史者40例作为对照组，两组年龄、性别无统计学差异。检测血浆总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）含量后作统计学比较。结果RV0病例组的血浆TC，TG和LDL-C水平较对照组显著升高（5．61±1．02，2．09±0．91，3．28±0．51mmol／Lvs4．26±0．91，1．26±0．9，2．68±0．48mmol／L，t=2．432，2．126，3．27，P均〈O．05），而HDL-C水平则显著低于对照组（1．08±0．46mmol／LVS1．76±0．62mmol／L，t=-2．33，P〈O．05）i病例组中CRV0及BRV0患者的血脂四项指标比较差异无统计学意义（P均〉0．05）。结论高脂血症为RVO的独立危险因素，降血脂药物应在治疗中被考虑使用。

Clinical Observation of Lipid Levels with Retinal Vein Occlusion

Objective To study retinal vein occlusion （RVO） changes in lipid levels in patients,to investigate whether elevat- ed blood lipids RVO an independent risk factor for the treatment and prevention of the disease, provide an objective basis. Methods A case-control study,40 patients diagnosed with RVO patients who did not receive treatment through medication as case group including central retinal vein occlusion （CRVO） were 28 people, branch retinal vein occlusion （BRVO） pa- tients with 12 people, physical examination and the past year no history of retinal vascular disease in 40 patients as the con- trol group,two groups of age, gender no difference. Statistical comparisons of plasma total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL-C）, low density hpoprotem cholesterol （LDL-C）. Results RVO case group plasma TC, TG,LDL-C mean significantly higher than the control group （P〈0.05） ,while HDL--C level was signifi- cantly lower than the control group （P〈0. 05） ;case group patients with CRVO and BRVO lipid four indicators showed no statistically significant （P〉0.05）. Conclusion hyperlipidemia is an independent risk factor for RVO,lipid-lowering drugs should be considered in the treatment.