| 二种纤维蛋白原测定方法的评价 |
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| 引用本文： | 杨绍信,熊玮平,王飙. 二种纤维蛋白原测定方法的评价[J]. 现代检验医学杂志, 2001, 16(2): 17-18 |
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| 作者姓名： | 杨绍信 熊玮平 王飙 |
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| 作者单位： | 西安市红十字会医院检验科, |
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| 摘 要： | 目的对Vonclauss法和PT衍算法(PT-der法)定量测定纤维蛋白原(Fbg)进行实验评价。方法低、中、高值质控血浆的批内精密度实验，对临床样本测定的统计学分析。结果Vonclauss法和PT-der法对样本的测定只有Fbg含量在2～3g/L时，测定结果才无统计学差异，在2g/L＞Fbg＞3g/L时均有显著性差异，PT-der法测得的结果偏高。结论建议在临床应用中不要以PT-der法代替Vonclauss法进行Fbg测定。
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| 关 键 词： | 纤维蛋白原；Vonclauss法；PT衍算法 |
| 文章编号： | 1005-1716(2001)02-017-02 |
| 修稿时间： | 2000-07-28 |
The Study of Two DifferentMethods of Fibrinogen Assays |
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| YANG Shao-xin,XIONG Wei-ping,WANG Biao. The Study of Two DifferentMethods of Fibrinogen Assays[J]. Journal of Modern Laboratory Medicine, 2001, 16(2): 17-18 |
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| Authors: | YANG Shao-xin XIONG Wei-ping WANG Biao |
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| Abstract: | Aim A preliminary study was made to evaluate two fibrinogen determination methods:Von clauss method and Prothrombin time derived method.Methods Three level of control plasma were determined repeatly to evaluate the precision of two methods.The result that obtained by two methods from daily work sample were statistically evaluated.Result There hadn't statistically significant difference by t test ( P <0 05) only when the concentration of fibrinogen is between 2 and 3g/L.For plasma with lower (<2g/L) or with high fibrinogen concentration (>3g/L ),the values had statistically significant difference. The PT derived method tend to overestimate the fibrinogen results compared to the Von clauss method.Conclusion In daily work,PT der method should not replace the Von clauss method in the fibrinogen assay. |
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| Keywords: | Fibrinogen Von clauss method PT der method |
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