| 阿托伐他汀对老年脑梗死伴高血脂患者颈动脉粥样硬化斑块的影响 |
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| 引用本文： | 耿桂玲,李忠梅,李以菊,常玉婷,杨延芳.阿托伐他汀对老年脑梗死伴高血脂患者颈动脉粥样硬化斑块的影响[J].中国临床实用医学,2010,4(2):117-119. |
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| 作者姓名： | 耿桂玲 李忠梅 李以菊 常玉婷 杨延芳 |
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| 作者单位： | 山东省泰山医学院附属聊城市二院药房南区药房,252600;山东省泰山医学院附属聊城市二院过敏原室,252600;山东省泰山医学院附属聊城市二院生殖医学,252600;山东省泰山医学院附属聊城市二院神经内科,252600; |
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| 摘 要： | Objective To investigate the effect of atorvastatin on arteriosclerosis plaque of carotid artery in elder patients with cerebral infarction and hypercholesterolemia. Methods With self-comparsion of before and after treatment,50 subjects with arteriosclerosis plaque of carotid artery were given atorvastatin 10 mg,qn for 12 months. After treatment 6 and 12 months, arteriosclerosis plaque of carotid artery、 intima-media thickness and peak index were measured in all patients. Results After 6 and 12 months adminstration of atorvastatin, TC、TG、LDL-C were all reduced (P<0.05), and HDL-C was elevated (P<0.01) in all patients.The initial diameter of carotid was significantly enlarged in 12 months (P<0.01). The size of plaque decreased (P<0.01) in 12 months after atorvastatin therapy than before(P<0.01). Conclusion The effect of atorvastatin is certain and it can stabilize the plaque of carotid artery.
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| 关 键 词： | 阿托伐他汀 脑梗死 高血脂 颈动脉粥样硬化斑块 |
Effect of atorvastatin on arteriosclerosis plaque of carotid artery in elder patients with cerebral infarction and hypercholesterolemia |
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| Abstract: | |
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| Keywords: | AtorvastatinCerebral infarctionHypercholesterolumiaArteriosclerosis plaque of carotid artery |
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