802例医院深部真菌感染临床调查

目的了解医院深部真菌感染的特点,为医院真菌感染控制提供依据。方法采用回顾性调查方法对绍兴市人民医院连续2年发生的医院真菌感染病例进行调查分析。结果该医院2006~2007年发生医院深部真菌感染患者802例,平均年龄63.3岁,均有基础疾病。感染部位以下呼吸道为主,占43.2%;感染真菌以白色念珠菌居多,占44.1%。所有患者均使用过抗生素,以第三代头孢菌素类和喹诺酮类为主。结论该医院深部真菌感染发生率较高,其主要危险因素是不合理使用抗生素,建议根据药敏试验结果合理选用抗生素。

CLINICAL INVESTIGATION OF 802 CASES OF NOSOCOMIAL DEEP FUNGAL INFECTION

Objective To know the clinical features of nosocomial deep fungal infections in order to provide the basis for controlling nosocomial fungal infection.Method Retrospective survey method was used to investigate and analyze the nosocomial fungal infection cases occurring in Shaoxing Municipal Hospital during 2 consecutive years.Results From 2006 through 2007,802 cases of nosocomial deep fungal infection occurred in this hospital.The average age of the patients was 63.3 years and all of them had underlying diseases.The infection site was mainly lower respiratory tract,accounting for 43.2%.The fungus causing infection was mostly Candida albicans,accounting for 44.1%.All patients had used antibiotics which were mainly third-generation cephailosporins and quinolones.Conclusions The incidence of nosocomial deep fungal infection in this hospital was relatively high and the main risk factor was irrational use of antibiotics.It is suggested to select antibiotics rationally according to the result of drug sensitivity test.