同型半胱氨酸联合颈动脉斑块检测用于早期诊断缺血性脑卒中的临床研究

目的 探讨同型半胱氨酸（Hcy）联合颈动脉斑块在早期缺血性脑卒中患者中的表现特征,以便为早期诊断提供依据.方法 早期缺血性脑卒中患者78例列入研究组,同期体检健康者80例列入对照组,两组患者均行Hcy和颈动脉斑块临床检测,并进行记录对比.结果 研究组患者Hcy浓度明显高于对照组,颈动脉内膜中层厚度明显厚于对照组,颈动脉斑块患病率明显高于对照组,差异有统计学意义（P〈0.05）.结论 Hcy浓度提高、存在颈动脉斑块和颈动脉内膜中层厚度增厚可作为临床早期诊断缺血性脑卒中的指标之一,可早期发现脑动脉血管状况不良的患者,并做好预防,减少临床脑梗死的发病,降低致残致死率.

Clinical study on joint detection of homocysteine and plaque of carotid artery in early diagnosis of patients with ischemic stroke

Objective To explore the significant characteristics of joint detection of homocysteine （Hcy） and plaque in carotid artery in patients with early ischemic stroke, in order to provide the basis for early diagnosis. Methods A total of 78 patients with early ischemic stroke were included in this study as study group, and 80 healthy controls in the same period in this hospital were included in control group, patients in these two groups were examined with Hcy and plaque in carotid artery and these data were recorded and compared. Results The concentration of Hcy in patients of study group was significantly higher, and the thickness of carotid intima media was significantly thicker than that of control group, the incidence of plaque in carotid artery was significantly higher, and the difference in these data was statistically significant （ P 〈 0.05 ）. Conclusion The increase in concentration of Hcy, the presence of plaque in carotid artery and thickening of carotid intima media can be used as indicators for early diagnosis of ischemic stroke, and they may be applied as the early signs for poor condition of cerebral arteries and it is impor tant to take measures to reduce the occurrence of cerebral infarction, and decrease the disability and death rate of these patients.