新生儿早期高胆红素血症病因与防治探讨

目的了解日龄≤7d住院新生儿高胆红素症的发病情况并进行临床分析。方法对2004年1月至2008年6月收治423例生后7d内新生儿高胆红素血症的发病原因及胆红素值进行分析。结果发病原因依次为围产因素、新生儿溶血、不明原因、感染因素、其它因素。该组病人占同期收治高胆红素血症组74．7％，早期蓝光光疗等综合治疗，可明显减少高胆红素血症及其并发症。结论防治高胆关键是加强围产期保健，早期蓝光光疗等综合治疗，可明显减少高胆及其并发症。

Study on etiopathogenesis, prevention and treatment of early hyperbilirubinaemia in newborns

Objective To investigate the incidence and clinical charactaristics of hyperbilirubinaemia in hospitalized neonates with age of less than or equal to 7 days old. Methods Retrospective analysis was done in 423 cases diagnosed as hyperbilirnbinaemia in their frist 7 days of life in this department from January 2004 to June 2008. Results The perinatal factors were the most common causes of hyperbilirnbinaemia, followed by neonatal hemolysis, unidentified reasons, infection and others. The number of these 423 cases accounted for 74.7% of newborns with hyperbilirubinaemia in the same period. The early phototherapy for neonates can significantly reduce the morbidity and complications of hyperbilirubinaemia. Conclusion Emphasis on perinatal care and early intervention with phototherapy for neonates are important measures for reducing the incidence and complications of hyperbilirubinacmia.