相对安全膀胱容量间歇导尿法保护上尿路的临床研究

目的探讨相对安全膀胱容量间歇导尿法防治脊髓损伤患者膀胱输尿管返流的疗效和适应证。方法23例男性完全性脊髓损伤患者，术后1个月～11年，年龄在7～45岁，其中对照组15例为无膀胱输尿管返流(VUR)，其他8例存在VUR，3例轻度返流，5例重度返流，依据患者相对安全膀胱容量的大小结合超声设备，对患者进行间歇导尿，每周测相对安全膀胱容量1次，治疗观察期2年以上。期间给予扩大膀胱容量的药物和方法以扩大膀胱容量。结果入院时无膀胱输尿管返流患者均未出现VUR；轻度返流者出现返流输尿管逐渐变细，返流程度逐渐减轻，直至返流消失；重度返流者返流未出现缓解。结论相对安全膀胱容量间歇导尿法对膀胱输尿管返流具有一定的防治作用。

Intermittent Catheterization by Relative Safe Bladder Capacity to Treat Vesical-ureteral Reflux

ObjectiveTo investigate the effects and indication of intermittent catheterization(IC) by relative safe bladder capacity(RSBC) to treat vesical-ureteral reflux(VUR).MethodsThere were 23 male complete SCI patients, aged between 7～45 years, including 15 patients without vesicao-ureteral reflux injuried 1～3 months as control group, 3 patients in mild group affected only ureter, and 5 patients in severe group affected not only ureter but also the pelvis. All the patients were taken intermittent catheterrization according to their own RSBC companied with supersonic device. The times of IC per day is that the average total urine volume one day was divided by RSBC. The observation time is over 2 years. During the oberservation some medicine was used to enlarge some patients bladder capacity.ResultsThere were no reflux in the control group; the reflux in the mild group improved a lot, some even disappeared, and there were no change in the severe group.ConclusionIC by RSBC is effective to prevent and cure vesical-ureteral reflux in some SCI patients.