艾司西酞普兰联合内观疗法治疗焦虑抑郁共病对照研究

目的：探讨艾司西酞普兰联合内观疗法治疗焦虑抑郁共病的临床效果。方法将63例焦虑抑郁共病患者按随机数字表法分为研究组32例，对照组31例，均予以艾司西酞普兰治疗，研究组在此基础上联合内观疗法治疗。观察4周。治疗前后采用汉密顿抑郁量表、汉密顿焦虑量表及临床疗效总评量表评定康复效果。结果治疗后研究组汉密顿抑郁量表、汉密顿焦虑量表及临床疗效总评量表评分均较治疗前显著降低(P <0.01)，研究组显著低于对照组(P<0.01)。结论艾司西酞普兰联合内观疗法治疗焦虑抑郁共病患者具有协同增效作用，疗效更显著，优于单用药物治疗。

A control study of escitalopram plus naikan therapy for co-morbid anxiety and depression

Objective To explore the efficacy of escitalopram plus naikan therapy for comorbid anxiety and depression (CAD).Methods Sixty-three CAD patients were assigned to research (n = 32)and control group (n =31)according to random number table,both groups treated with escitalopram,and on this ba-sis research group was plus naikan therapy for 4 weeks.Rehabilitation outcomes were assessed with the Hamilton Depression Scale (HAMD),Hamilton Anxiety Scale (HAMA)and Clinical Global Impression Scale (CGI)before and after treatment.Results After treatment the HAMD,HAMA and CGI score lowered more significantly compared with pretreatment in research group (P <0.01)and were significant-ly lower than those in control group (P <0.01).Conclusion Escitalopram plus naikan therapy has a syn-ergism and evident effect compared with single medication in CAD patients.