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Efficient polymer nanoparticle-mediated delivery of gene editing reagents into human hematopoietic stem and progenitor cells
Institution:1. Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA;2. Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA;3. Department of Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA
Abstract:
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  • Keywords:polymeric nanoparticles  hematopoietic stem cells  gene editing nucleases  gene therapy  lyophilization  quality control standards
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