爱婴病房艾条熏蒸对HBsAg灭活效果的研究

目的：弄清爱婴病房艾条熏蒸对病毒的灭活效果。方法：爱婴病房采用艾条熏蒸进行空气消毒，通过ＥＬＩＳＡ检测熏蒸后对乙肝病毒ＨＢｓＡｇ 和ＨＢｅＡｇ 抗原性的破坏效果，并与过氧乙酸熏蒸效果进行了对比试验。结果：爱婴病房艾条熏蒸后对乙肝病毒ＨＢｓＡｇ 的抗原性有明显的破坏作用（ Ｐ＜ ０．０５） ，对ＨＢｅＡｇ 的抗原性的破坏有极显著性意义（ Ｐ＜ ０．００１），Ｓ／Ｎ 比值＞ ２．１ ；过氧乙酸熏蒸后对ＨＢｓＡｇ 和ＨＢｅＡｇ 的抗原性的破坏均具有极显著性差异（ Ｐ＜ ０．００１），Ｓ／Ｎ 比值均＜ ２．１ ；艾条熏蒸组明显低于过氧乙酸熏蒸组对ＨＢｓＡｇ 和ＨＢｅＡｇ 抗原性的破坏作用，差异有极显著意义（ Ｐ＜ ０ ．００１） 。结论：爱婴病房艾条熏蒸对乙肝病毒ＨＢｓＡｇ 和ＨＢｅＡｇ 均有一定的灭活效果，但不能达到对乙肝病毒完全灭活的目的，不可代替过氧乙酸等消毒剂对病毒的灭活作用，可用于爱婴病房的空气消毒。

Study on Effect of Inactivation to HBsAg by Using of Moxa Fumigation in Baby-friendly Ward

Objective:to study the effect of inactivation to virus by using of moxa fumigation in baby friendly ward.Method:air disinfection of ward was carried out by moxa fumigation,destructive effect on antigenicity of HBsAg and HBeAg was tested by ELISA,and the experimentation was compared with peroxyacetic acid fumigation.Results:moxa fumigation had certain destructive effect on antigenicity of HBsAg (P<0.05),and had significantly destructive effect on antigenicity of HBeAg (P<0.001) ,S/N> 2.1 ;peroxyacetic acid fumigation had significant destructive effect on antigenicity of HBsAg and HBeAg (P<0.001),S/N<2.1;moxa fumigation group had significant less destructive effect to antigenicity of HBsAg and HBeAg in comparison with peroxyacetic acid fumigation group(P<0.001).Conclusion:moxa fumigation in ward had a certain inactivation effect to HBsAg and HBeAg,but didn't completely inactivate HBV,didn't replace disinfectants (peroxyacetic acid) on inactivation to virus,and may be used in air disinfection of baby friendly ward. Author's address The Second Affiliate Hospital of Guangzhou Medical College,Guangzhou,510260