不同浓度肝素钠溶液封管与锁骨下静脉导管堵塞的关系

目的 探讨不同浓度肝素钠溶液封管与锁骨下静脉留置管堵塞关系.方法 对进行锁骨下静脉穿刺置管术的肿瘤患者共889例,分A、B两组进行观察,A组在输液前后用肝素钠盐水(50μ/ml)5 ml冲管,B组肿瘤患者输液前后用肝素钠盐水(125μ/ml)5 ml冲管,两者均采用正压封管.统计学方法采用x2检验.结果 A组导管堵塞发生率为5.55%,B组导管堵塞发生率为1.13%,两者比较有显著性差异(P＜0.01).结论 应用不同浓度肝素钠溶液冲管与导管堵塞有关系,研究结果表明,用肝素钠盐水(125μ/ml)5 ml冲管能有效降低导管堵塞发生率.

The relationship of sealing catheter with different concentration of heparin sodium and obstruction after percutaneous insertion of subclavian venous catheters

Objective To investigate the relationship of sealing catheter with different concentration of heparin sodium and obstruction after percutaneous insertion of subclavian venous catheters.Methods A total of 889 cases of tumor with percutaneous insertion of subclavian venous catheters were individed into two groups, group A was flushed with (50 U/ml) 5 ml heparin sodium before and after infusion,and group B were flushed with (50 U/ml) 5 ml heparin sodium before and after infusion.Results 5.55% (25/889) of catheter obstruction in group A were occurred and 1.13% (5/889) of catheter obstruction in group B were occurred, there wss signification difference between the two groups (P ＜0.05) .Conclusions There is an obvious relationship of sealing catheter with different concentration of heparin sodium and obstruction after percutaneous insertion of subclavian venous catheters.Flushing catheter with 125 U/ml heparin sodium can reduce thecatheter obstruction rate effectively.